{"doi":"10.1038/npp.2013.260","title":"Hippocampal and Amygdalar Volumetric Differences in Pathological Gambling: a Preliminary Study of the Associations with the Behavioral Inhibition System","abstract":null,"journal":"Neuropsychopharmacology","year":2014,"id":650229,"datarank":0.6907755278982138,"base_score":4.605170185988092,"endowment":4.605170185988092,"self_citation_contribution":0.6907755278982138,"citation_network_contribution":0.0,"self_endowment_contribution":0.6907755278982138,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":99,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":871537,"name":"Jiansong Xu","orcid":"0000-0002-2708-2996","position":1,"is_corresponding":false},{"id":1695363,"name":"Marc N Potenza","orcid":null,"position":2,"is_corresponding":false},{"id":1695360,"name":"Ardeshir S Rahman","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Hippocampal and Amygdalar Volumetric Differences in Pathological Gambling: a Preliminary Study of the Associations with the Behavioral Inhibition System","abstract":"The behavioral inhibition system (BIS) and behavioral activation system (BAS) are hypothesized to underlie motivated behavior, relate to hippocampal and amygdalar function, and link to pathological gambling (PG). Prior studies have not investigated hippocampal and amygdalar volumes in PG and their relationships to BIS/BAS measures. Structural MRI scans and BIS/BAS and other clinical measures were obtained from 32 PG individuals and 47 healthy comparison (HC) individuals. Volumetric measures of the hippocampus and amygdala were assessed using FreeSurfer and related to BIS/BAS measures. PG relative to HC individuals demonstrated diminished volume in the left hippocampus and right amygdala and higher BIS and BAS scores. BIS scores were positively correlated with left hippocampal and left amygdalar volumes in PG individuals. The findings of relatively diminished hippocampal and amygdalar volumes in PG individuals resonate with findings from substance-dependent groups. Relationships between amygdalar and hippocampal volumes and BIS measures in PG suggest that individual differences in these structures may contribute to avoidance behaviors in PG.","is_dataset_classified":null,"base_score":4.605170185988092,"endowment":4.605170185988092,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"24077065","pmcid":"PMC3895252","openalex_id":"https://openalex.org/W2082405250","authors":[],"funders":[{"funder_name":"NIDA NIH HHS","grant_id":"R01 DA019039","title":null},{"funder_name":"NIAAA NIH HHS","grant_id":"RL1 AA017539","title":null},{"funder_name":"NIDA NIH HHS","grant_id":"P20 DA027844","title":null},{"funder_name":"NIDA NIH HHS","grant_id":"K01 DA027750","title":null},{"funder_name":"National Institutes of Health","grant_id":"5P20DA027844-04","title":"Clinical and Educational Core"},{"funder_name":"National Institutes of Health","grant_id":"5R01DA019039-05","title":"fMRI of Craving in Addictions: Gender Differences"},{"funder_name":"National Institutes of Health","grant_id":"5K01DA027750-05","title":"FMRI & DTI Study on Neural Predictor of Treatment Outcome of Cocaine Dependence"},{"funder_name":"National Institutes of Health","grant_id":"5RL1AA017539-02","title":"fMRI of Stress & Self-Control in Smoking & Obesity (7 of 14)"}],"total_grants":8,"fwci":4.808,"citation_percentile":0.94250263,"influential_citations":0,"citation_trend":[{"year":2014,"count":5},{"year":2015,"count":5},{"year":2016,"count":4},{"year":2017,"count":5},{"year":2018,"count":5},{"year":2019,"count":3},{"year":2020,"count":50},{"year":2021,"count":4},{"year":2022,"count":9},{"year":2023,"count":6},{"year":2024,"count":1},{"year":2025,"count":2}],"oa_status":"bronze","license":"Springer TDM","oa_locations":[{"url":"https://www.nature.com/articles/npp2013260.pdf","host_type":"journal"},{"url":"https://www.nature.com/articles/npp2013260.pdf","host_type":"publisher"},{"url":"http://www.nature.com/articles/npp2013260.pdf","host_type":"publisher"},{"url":"http://www.nature.com/articles/npp2013260","host_type":"publisher"},{"url":"https://doi.org/10.1038/npp.2013.260","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/24077065","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3895252","host_type":"repository"},{"url":"https://dx.doi.org/10.1038/npp.2013.260","host_type":""}],"fields_of_study":["Gambling Behavior and Treatments","Schizophrenia research and treatment","Obsessive-Compulsive Spectrum Disorders","03 medical and health sciences","0302 clinical medicine","Adult","Amygdala","Anxiety","Female","Gambling","Hippocampus","Humans","Image Processing, Computer-Assisted","Magnetic Resonance Imaging","Male","Regression Analysis","Statistics as Topic"],"mesh_terms":["Adult","Amygdala","Anxiety","Female","Gambling","Hippocampus","Humans","Image Processing, Computer-Assisted","Magnetic Resonance Imaging","Male","Regression Analysis","Statistics as Topic"],"keywords":["Hippocampal formation","Amygdala","Hippocampus","Psychology","Pathological","Neuroscience","Internal medicine","Medicine","Adult","Male","Statistics as Topic","Anxiety","Magnetic Resonance Imaging","Gambling","Image Processing, Computer-Assisted","Humans","Regression Analysis","Female"],"sdg_mappings":[{"sdg_number":7,"sdg_label":"7. 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