{"doi":"10.1038/ni.3006","title":"High-dimensional analysis of the murine myeloid cell system","abstract":null,"journal":"Nature Immunology","year":2014,"id":594079,"datarank":0.887834078140972,"base_score":5.918893854273146,"endowment":5.918893854273146,"self_citation_contribution":0.887834078140972,"citation_network_contribution":0.0,"self_endowment_contribution":0.887834078140972,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":371,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":104387,"name":"Andreas Schlitzer","orcid":"0000-0001-7662-3712","position":1,"is_corresponding":false},{"id":1198952,"name":"Jinmiao Chen","orcid":"0000-0001-7547-6423","position":2,"is_corresponding":false},{"id":272535,"name":"Florian Mair","orcid":"0000-0001-6732-5449","position":3,"is_corresponding":false},{"id":1520622,"name":"Hermi R Sumatoh","orcid":null,"position":4,"is_corresponding":false},{"id":1520623,"name":"Karen Wei Weng Teng","orcid":null,"position":5,"is_corresponding":false},{"id":1520625,"name":"Donovan Low","orcid":null,"position":6,"is_corresponding":false},{"id":878282,"name":"Christiane Ruedl","orcid":"0000-0002-5599-6541","position":7,"is_corresponding":false},{"id":1520629,"name":"Paola Riccardi-Castagnoli","orcid":null,"position":8,"is_corresponding":false},{"id":189937,"name":"Michael Poidinger","orcid":"0000-0002-1047-2277","position":9,"is_corresponding":false},{"id":297350,"name":"Melanie Greter","orcid":"0000-0002-7220-5369","position":10,"is_corresponding":false},{"id":71133,"name":"Florent Ginhoux","orcid":"0000-0002-2857-7755","position":11,"is_corresponding":false},{"id":272540,"name":"Evan W. 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In addition to identifying all previously described myeloid populations, higher-order analysis allowed objective delineation of otherwise ambiguous subsets, including monocyte-macrophage intermediates and an array of granulocyte variants. Using mice that cannot sense granulocyte macrophage-colony stimulating factor GM-CSF (Csf2rb(-/-)), which have discrete alterations in myeloid development, we confirmed differences in barrier tissue dendritic cells, lung macrophages and eosinophils. The methodology further identified variations in the monocyte and innate lymphoid cell compartment that were unexpected, which confirmed that this approach is a powerful tool for unambiguous and unbiased characterization of the myeloid system.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"25306126","pmcid":null,"openalex_id":null,"authors":[],"funders":[{"funder_name":"Swiss National Science Foundation","grant_id":"136203","title":"The interplay between innate and adaptive tumor-specific immune responses induced through local tumor therapy in skin cancer"},{"funder_name":"Swiss National Science Foundation","grant_id":"144781","title":"The role of interleukin-34 for the development and function of the mononuclear phagocyte system during the steady state and inflammation"},{"funder_name":"Swiss National Science Foundation","grant_id":"146130","title":"The role of the NF?B-inducing kinase NIK in the development and function of cellular immunity"}],"total_grants":3,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"closed","license":"Springer TDM","oa_locations":[{"url":"http://www.nature.com/articles/ni.3006.pdf","host_type":"publisher"},{"url":"http://www.nature.com/articles/ni.3006","host_type":"publisher"},{"url":"https://doi.org/10.1038/ni.3006","host_type":""},{"url":"https://pubmed.ncbi.nlm.nih.gov/25306126","host_type":""},{"url":"https://dx.doi.org/10.1038/ni.3006","host_type":""},{"url":"https://sonar.ch/global/documents/35909","host_type":""},{"url":"https://doi.org/10.5167/uzh-102048","host_type":""},{"url":"https://www.zora.uzh.ch/id/eprint/102048/","host_type":""},{"url":"http://dx.doi.org/10.1038/ni.3006","host_type":""}],"fields_of_study":["03 medical and health sciences","0302 clinical medicine"],"mesh_terms":["Myeloid Cells","Animals","Mice, Inbred C57BL","Mice","Flow Cytometry","Cluster Analysis","Artificial Intelligence"],"keywords":["2403 Immunology","610 Medicine & health","10263 Institute of Experimental Immunology","Flow Cytometry","Mice, Inbred C57BL","Mice","Artificial Intelligence","2723 Immunology and Allergy","570 Life sciences; biology","Animals","Cluster Analysis","Myeloid Cells"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-27T13:26:18.116650Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}