{"doi":"10.1037/neu0001021","title":"Affliction class moderates the dementing impact of amyloidopathy.","abstract":"OBJECTIVE: The treatment of dementia is increasingly likely to focus on dementia-related biomarkers. Unfortunately, there is variability with regard to biomarker-related effects. This analysis tests an algorithm capable of identifying persons adversely impacted by any dementia-related biomarker in this case, amyloidopathy as estimated by positron emission tomography (PET). METHOD: = 1,737 subjects of the Alzheimer's disease neuroimaging initiative were assigned to amyloidopathy-affliction classes. Moderation effects were tested by chi-square difference. RESULTS: = .05. PET assessed amyloid burden was not related to dementia severity in resilient PET (+) cases. CONCLUSION: Our approach could allow for more accurate prediction of biomarker effects and guide precision interventions against specific biomarkers. (PsycInfo Database Record (c) 2025 APA, all rights reserved).","journal":"Neuropsychology","year":2025,"id":541902,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.7141,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":632831,"name":"Raymond F. Palmer","orcid":"0000-0001-6621-9038","position":1,"is_corresponding":false},{"id":905122,"name":"Donald R. Royall","orcid":"0000-0001-6475-0300","position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":null,"created_at":"2026-07-19T02:52:51.593043Z","pmid":"40720331","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}