{"doi":"10.1021/ol016394w","title":"Novel Peptidomimetics of the Antifungal Cyclic Peptide Rhodopeptin:  Synthesis of Mimetics and Their Antifungal Activity","abstract":null,"journal":"Organic Letters","year":2001,"id":685918,"datarank":0.515098080672772,"base_score":3.4339872044851463,"endowment":3.4339872044851463,"self_citation_contribution":0.515098080672772,"citation_network_contribution":0.0,"self_endowment_contribution":0.515098080672772,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":30,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":199685,"name":"Kiyoshi Nakayama","orcid":null,"position":1,"is_corresponding":false},{"id":1136422,"name":"Hiroaki Inagaki","orcid":null,"position":2,"is_corresponding":false},{"id":1792039,"name":"Toshiharu Ohta","orcid":null,"position":3,"is_corresponding":false},{"id":1792035,"name":"Haruko C. Kawato","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Novel Peptidomimetics of the Antifungal Cyclic Peptide Rhodopeptin:  Synthesis of Mimetics and Their Antifungal Activity","abstract":"[reaction: see text]. Novel peptidomimetics of the antifungal cyclic peptide Rhodopeptin were synthesized. As with the cyclic peptides, the presence of all three Rhodopeptin side chains was found to be indispensable for peptidomimetic activity. We discovered new compounds exhibiting greater antifungal activity and improved physiochemical properties in comparison to the parent compounds.","is_dataset_classified":null,"base_score":3.4339872044851463,"endowment":3.4339872044851463,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"11678680","pmcid":null,"openalex_id":"https://openalex.org/W2951692049","authors":[],"funders":[],"total_grants":0,"fwci":2.9992,"citation_percentile":0.90938652,"influential_citations":0,"citation_trend":[{"year":2014,"count":2},{"year":2016,"count":1},{"year":2025,"count":3}],"oa_status":"closed","license":null,"oa_locations":[{"url":"https://pubs.acs.org/doi/pdf/10.1021/ol016394w","host_type":"publisher"},{"url":"https://doi.org/10.1021/ol016394w","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/11678680","host_type":"repository"}],"fields_of_study":["Antimicrobial Peptides and Activities","Biochemical and Structural Characterization","Carbohydrate Chemistry and Synthesis","Alkanes","Antifungal Agents","Benzimidazoles","Benzodiazepines","Fungi","Glucosamine","Heterocyclic Compounds, 1-Ring","Hydantoins","Microbial Sensitivity Tests","Models, Molecular","Molecular Mimicry","Oligopeptides","Solubility","Structure-Activity Relationship"],"mesh_terms":["Alkanes","Antifungal Agents","Benzimidazoles","Benzodiazepines","Fungi","Glucosamine","Heterocyclic Compounds, 1-Ring","Hydantoins","Microbial Sensitivity Tests","Models, Molecular","Oligopeptides","Solubility","Structure-Activity Relationship","Molecular Mimicry"],"keywords":["Peptidomimetic","Antifungal","Chemistry","Cyclic peptide","Peptide","Combinatorial chemistry","Stereochemistry","Biological activity","Biochemistry","In vitro","Microbiology","Biology"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-18T18:02:47.530641Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}