{"doi":"10.1021/acsinfecdis.2c00082","title":"Glycomic Analysis Reveals a Conserved Response to Bacterial Sepsis Induced by Different Bacterial Pathogens","abstract":"-glycan shift. Analysis of this band by mass spectrometry identified interalpha-trypsin inhibitor heavy chains (ITIHs) and fibronectin, both of which are associated with human sepsis. Shifts in the glycosylation of these proteins were observed. Overall, our work points toward a common mechanism for bacterially induced sepsis, marked by conserved changes in the glycome.","journal":"ACS Infectious Diseases","year":2022,"id":245012,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":25,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9521,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":574975,"name":"Shuhui Chen","orcid":"0000-0001-7255-0026","position":1,"is_corresponding":false},{"id":879399,"name":"Peter V. Aziz","orcid":"0000-0001-8957-100X","position":2,"is_corresponding":false},{"id":879400,"name":"JH Chung","orcid":"0009-0009-2373-3307","position":3,"is_corresponding":false},{"id":266074,"name":"Jamey D. Marth","orcid":"0000-0001-9323-1649","position":4,"is_corresponding":false},{"id":456104,"name":"Lara K. Mahal","orcid":"0000-0003-4791-8524","position":5,"is_corresponding":false},{"id":456103,"name":"Daniel W. Heindel","orcid":"0000-0002-4760-4501","position":0,"is_corresponding":true}],"reference_count":46,"raw_metadata":null,"created_at":"2026-07-19T00:23:34.974895Z","pmid":"35486714","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}