{"doi":"10.1021/acs.orglett.5c03477","title":"Total Synthesis of Honokiol via Oxidative Phenol Coupling","abstract":"Herein we disclose the total synthesis of honokiol in six steps in an overall yield of 66%. Two distinct routes were explored, with the key steps being highly efficient and selective cross-couplings of commercially available phenols to construct the main biphenolic backbone. The routes employ inexpensive reagents and are scalable, high-yielding processes. The experimental procedures are reported in the conventional narrative format and two machine-readable formats.","journal":"Organic Letters","year":2025,"id":577343,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9383,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1486478,"name":"Young Eun Lee","orcid":"0009-0009-6199-898X","position":1,"is_corresponding":false},{"id":642067,"name":"Sun Min Kim","orcid":"0000-0001-8420-637X","position":2,"is_corresponding":false},{"id":1486888,"name":"Stanislav Jaracz","orcid":null,"position":3,"is_corresponding":false},{"id":325869,"name":"Marisa C. Kozlowski","orcid":"0000-0002-4225-7125","position":4,"is_corresponding":false},{"id":1408028,"name":"Elso Manuel Cruz Cruz","orcid":"0009-0008-8053-0306","position":0,"is_corresponding":true}],"reference_count":32,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T02:58:04.622308Z","pmid":"41065454","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}