{"doi":"10.1021/acs.orglett.0c02847","title":"A Diversity-Oriented Strategy for Chemoenzymatic Synthesis of Glycosphingolipids and Related Derivatives","abstract":"A diversity-oriented strategy combining enzymatic glycan assembly and on-site lipid remodeling via chemoselective cross-metathesis and N-acylation was developed for glycosphingolipid (GSL) synthesis starting from a common, simple glycoside. The strategy was verified with a series of natural GSLs and GSL derivatives and showed several advantages. Most notably, it enabled two-way diversification of the glycan and lipid, including introduction of designed molecular tags, to provide functionalized GSLs useful for biological studies and applications.","journal":"Organic Letters","year":2020,"id":78261,"datarank":0.8100858260654681,"base_score":2.9444389791664403,"endowment":2.9444389791664403,"self_citation_contribution":0.44166584687496613,"citation_network_contribution":0.36841997919050196,"self_endowment_contribution":0.44166584687496613,"citer_contribution":0.36841997919050196,"corpus_percentile":null,"corpus_rank":null,"citation_count":18,"citer_count":13,"citers_with_citation_signal":12,"citers_with_endowment":12,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9497,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":408192,"name":"Mohit Jaiswal","orcid":null,"position":1,"is_corresponding":false},{"id":407225,"name":"Rajendra Rohokale","orcid":"0000-0001-8083-0466","position":2,"is_corresponding":false},{"id":407226,"name":"Zhongwu Guo","orcid":"0000-0001-5302-6456","position":3,"is_corresponding":false},{"id":407224,"name":"Qingjiang Li","orcid":"0000-0001-5535-6993","position":0,"is_corresponding":true}],"reference_count":38,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-18T21:49:40.769098Z","pmid":"33074681","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}