{"doi":"10.1021/acs.macromol.4c00315","title":"Molecularly Shielded, On-Demand, Ultrasound-Cured Polymer Networks","abstract":"Networks formed from polymers can range from soft hydrogels to ultrahard protective coatings, making them useful for a wide range of applications, from cell culture to highly bonded adhesives. Polymer networks are commonly cross-linked via heat or high-energy light, and recently mechanical force has also been used to induce the formation of cross-links in preexisting networks. Here, we demonstrate a new strategy to use mechanical deformation and ultrasound to induce liquid-to-solid cross-linking. We synthesized graft copolymers with large poly(ethylene glycol) (PEG) side chains acting as molecular shielding groups to protect otherwise highly reactive epoxide groups. Solutions of highly shielded polymers could remain as a liquid solution when left undisturbed, and we could initiate gelation of these solutions with ultrasound in 20 s. These ultrasound-sensitive polymers are particularly useful in light- and heat-sensitive applications and where precise control over the gelation time is required.","journal":"Macromolecules","year":2024,"id":468508,"datarank":0.20794415416798362,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"self_citation_contribution":0.20794415416798362,"citation_network_contribution":0.0,"self_endowment_contribution":0.20794415416798362,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.95,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1301605,"name":"Hsu Shwe Yee Naing","orcid":"0009-0001-6564-2827","position":1,"is_corresponding":false},{"id":1302046,"name":"Jichao Song","orcid":null,"position":2,"is_corresponding":false},{"id":469232,"name":"Jessica D. Schiffman","orcid":"0000-0002-1265-5392","position":3,"is_corresponding":false},{"id":1301606,"name":"John Klier","orcid":"0000-0002-0506-0518","position":4,"is_corresponding":false},{"id":299448,"name":"Shelly R. Peyton","orcid":"0000-0002-7364-8727","position":5,"is_corresponding":false},{"id":1228663,"name":"Adrian Lorenzana","orcid":"0000-0002-6517-6897","position":0,"is_corresponding":true}],"reference_count":54,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T02:05:23.500722Z","pmid":"40600004","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}