{"doi":"10.1021/acs.jproteome.6b00066","title":"Evaluation and Improvement of Quantification Accuracy in Isobaric Mass Tag-Based Protein Quantification Experiments","abstract":null,"journal":"Journal of Proteome Research","year":2016,"id":21736,"datarank":3.8959221895486187,"base_score":5.209486152841421,"endowment":5.209486152841421,"self_citation_contribution":0.7814229229262133,"citation_network_contribution":3.1144992666224054,"self_endowment_contribution":0.7814229229262133,"citer_contribution":3.1144992666224054,"corpus_percentile":null,"corpus_rank":null,"citation_count":182,"citer_count":118,"citers_with_citation_signal":86,"citers_with_endowment":86,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":55.0,"fair_percentile":80.29903254177661,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":138889,"name":"Timo Glatter","orcid":null,"position":1,"is_corresponding":false},{"id":138890,"name":"Cristina Viganò","orcid":null,"position":2,"is_corresponding":false},{"id":138891,"name":"Conrad von Schubert","orcid":null,"position":3,"is_corresponding":false},{"id":138892,"name":"Erich A. Nigg","orcid":null,"position":4,"is_corresponding":false},{"id":138893,"name":"Alexander Schmidt","orcid":null,"position":5,"is_corresponding":false},{"id":138888,"name":"Erik Ahrné","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":5.209486152841421,"endowment":5.209486152841421,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"27345528","pmcid":null,"openalex_id":"https://openalex.org/W2465149832","authors":[],"funders":[{"funder_name":"Swiss National Science Foundation","grant_id":"310030B_149641","title":null},{"funder_name":"Swiss National Science Foundation","grant_id":"149641","title":"Control of centrosome duplication and chromosome segregation"}],"total_grants":2,"fwci":10.6548,"citation_percentile":0.98938789,"influential_citations":14,"citation_trend":[{"year":2017,"count":11},{"year":2018,"count":16},{"year":2019,"count":19},{"year":2020,"count":18},{"year":2021,"count":16},{"year":2022,"count":28},{"year":2023,"count":31},{"year":2024,"count":16},{"year":2025,"count":18},{"year":2026,"count":9}],"oa_status":"closed","license":null,"oa_locations":[{"url":"https://figshare.com/articles/journal_contribution/Evaluation_and_Improvement_of_Quantification_Accuracy_in_Isobaric_Mass_Tag-Based_Protein_Quantification_Experiments/3473945/1/files/5470025.pdf","host_type":"GREEN"},{"url":"https://pubs.acs.org/doi/pdf/10.1021/acs.jproteome.6b00066","host_type":"publisher"},{"url":"https://doi.org/10.1021/acs.jproteome.6b00066","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/27345528","host_type":"repository"},{"url":"https://dx.doi.org/10.1021/acs.jproteome.6b00066","host_type":""},{"url":"https://sonar.ch/global/documents/92517","host_type":""},{"url":"http://hdl.handle.net/21.11116/0000-000C-0429-2","host_type":""},{"url":"http://pubs.acs.org/doi/abs/10.1021/acs.jproteome.6b00066","host_type":""},{"url":"https://doi.org/https://doi.org/10.1021/acs.jproteome.6b00066","host_type":""}],"fields_of_study":["Advanced Proteomics Techniques and Applications","Mass Spectrometry Techniques and Applications","Biosensors and Analytical Detection","Medicine","Chemistry","0301 basic medicine","03 medical and health sciences","Cell Line","Cell Line, Tumor","Data Interpretation, Statistical","Escherichia coli","Humans","Proteome","Proteomics","Tandem Mass Spectrometry"],"mesh_terms":["Cell Line","Data Interpretation, Statistical","Escherichia coli","Humans","Proteome","Proteomics","Cell Line, Tumor","Tandem Mass Spectrometry"],"keywords":["Isobaric labeling","Isobaric process","Tandem mass tag","Quantitative proteomics","Label-free quantification","Proteome","Chromatography","Mass spectrometry","Chemistry","Tandem mass spectrometry","Proteomics","Biological system","Computer science","Computational biology","Analytical Chemistry (journal)","Biology","Protein mass spectrometry","Biochemistry","Itraq","Tmt","Quantitative Mass Spectrometry","Cell Line","Cell Line, Tumor","Data Interpretation, Statistical","Escherichia coli","Humans"],"sdg_mappings":[{"sdg_number":3,"sdg_label":"3. Good health"},{"sdg_number":13,"sdg_label":"13. Climate action"},{"sdg_number":0,"sdg_label":"Life below water"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[{"name":"pxd"}],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-06T16:40:20.580845Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":100.0,"fair_a":70.0,"fair_i":50.0,"fair_r":0.0,"fair_zscore":0.8854,"fair_rationale":{"fair_score":55.0,"has_llm":false,"dimensions":{"F":{"name":"Findable","score":100.0,"criteria":[{"key":"f_has_doi","label":"Has a persistent DOI","kind":"deterministic","weight":1.0,"fraction":1.0,"signal":"DOI present","rationale":null},{"key":"f_repository_presence","label":"Indexed in repositories / literature DBs","kind":"deterministic","weight":1.0,"fraction":1.0,"signal":"datacite=0, pmcid=False, pmid=True","rationale":null},{"key":"f_persistent_ids","label":"Resolvable scholarly identifiers (OpenAlex)","kind":"deterministic","weight":0.5,"fraction":1.0,"signal":"OpenAlex id present","rationale":null}]},"A":{"name":"Accessible","score":70.0,"criteria":[{"key":"a_open_access","label":"Open Access / files deposited","kind":"deterministic","weight":1.5,"fraction":0.5,"signal":"files/OA location present but not flagged OA","rationale":null},{"key":"a_retrievable","label":"Free full text retrievable","kind":"deterministic","weight":1.0,"fraction":1.0,"signal":"9 OA location(s)","rationale":null}]},"I":{"name":"Interoperable","score":50.0,"criteria":[{"key":"i_linked_data","label":"Linked datasets / DataCite relations","kind":"deterministic","weight":1.0,"fraction":0.0,"signal":"linked_datasets=0, datacite=0","rationale":null},{"key":"i_standard_ids","label":"References data via standard accessions","kind":"deterministic","weight":1.0,"fraction":1.0,"signal":"accessions=1, trials=0","rationale":null}]},"R":{"name":"Reusable","score":0.0,"criteria":[{"key":"r_license","label":"Clear, open reuse license","kind":"deterministic","weight":1.5,"fraction":0.0,"signal":"no license","rationale":null},{"key":"r_downloads","label":"Demonstrated reuse (downloads)","kind":"deterministic","weight":0.5,"fraction":0.0,"signal":"downloads=0","rationale":null},{"key":"r_version","label":"Versioned / maintained","kind":"deterministic","weight":0.5,"fraction":0.0,"signal":"no version chain","rationale":null},{"key":"r_dataset","label":"Classified as a data resource","kind":"deterministic","weight":0.5,"fraction":0.0,"signal":"not a dataset","rationale":null}]}},"suggestions":["Attach a clear, open reuse license (e.g. CC-BY or CC0).","Link the underlying datasets via DOIs / DataCite relations.","Maintain explicit versioning for the dataset.","Make the paper/data Open Access or deposit the files in an open repository."],"model":null,"agent_version":"fair_agent_v1","fulltext_source":"none"},"fair_model":null,"fair_agent_version":"fair_agent_v1","fair_fulltext_source":"none","fair_has_llm":false,"fair_computed_at":"2026-06-11T21:47:22.824906Z","clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}