{"doi":"10.1017/s2040174423000089","title":"Associations of maternal preterm birth with subsequent risk for type 2 diabetes in women from the women’s health initiative","abstract":"Abstract Preterm birth has been associated with insulin resistance and beta-cell dysfunction, a hallmark characteristic of type 2 diabetes. However, studies investigating the relationship between a personal history of being born preterm and type 2 diabetes are sparse. We sought to investigate the potential association between a personal history of being born preterm and risk for type 2 diabetes in a racially and ethnically diverse population. Baseline and incident data (>16 years of follow-up) from the Women’s Health Initiative ( n = 85,356) were used to examine the association between personal history of being born preterm (born 1910–1940s) and prevalent (baseline enrollment; cross-sectional) or incident (prospective cohort) cases of type 2 diabetes. Logistic and Cox proportional hazards regression models were used to estimate odds and hazards ratios. Being born preterm was significantly, positively associated with odds for prevalent type 2 diabetes at enrollment (adjOR = 1.79, 95% CI 1.43–2.24; P < 0.0001). Stratified regression models suggested the positive associations at baseline were consistent across race and ethnicity groups. However, being born preterm was not significantly associated with risk for incident type 2 diabetes. Regression models stratified by age at enrollment suggest the relationship between being born preterm and type 2 diabetes persists only among younger age groups. Preterm birth was associated with higher risk of type 2 diabetes but only in those diagnosed with type 2 diabetes prior to study enrollment, suggesting the association between preterm birth and type 2 diabetes may exist at earlier age of diagnosis but wane over time.","journal":"Journal of Developmental Origins of Health and Disease","year":2023,"id":365477,"datarank":0.29188652235829704,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"self_citation_contribution":0.29188652235829704,"citation_network_contribution":0.0,"self_endowment_contribution":0.29188652235829704,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9519,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":774008,"name":"Brian Monahan","orcid":"0000-0003-3212-430X","position":1,"is_corresponding":false},{"id":249046,"name":"Erin S. LeBlanc","orcid":"0000-0002-4067-3432","position":2,"is_corresponding":false},{"id":281196,"name":"Simin Liu","orcid":"0000-0003-2098-3844","position":3,"is_corresponding":false},{"id":305546,"name":"Rami Nassir","orcid":"0000-0001-9914-7851","position":4,"is_corresponding":false},{"id":11827,"name":"Nazmus Saquib","orcid":"0000-0002-2819-2839","position":5,"is_corresponding":false},{"id":505622,"name":"Peter F. Schnatz","orcid":null,"position":6,"is_corresponding":false},{"id":272433,"name":"Aladdin H. Shadyab","orcid":"0000-0002-9693-0522","position":7,"is_corresponding":false},{"id":531660,"name":"Rachel Sinkey","orcid":"0000-0001-7674-9796","position":8,"is_corresponding":false},{"id":243122,"name":"Jean Wactawski‐Wende","orcid":"0000-0003-3096-9595","position":9,"is_corresponding":false},{"id":247249,"name":"Robert A. Wild","orcid":"0000-0002-1298-265X","position":10,"is_corresponding":false},{"id":413531,"name":"Lisa Chasan‐Taber","orcid":"0000-0002-2809-0744","position":11,"is_corresponding":false},{"id":11268,"name":"JoAnn E. Manson","orcid":"0000-0002-9426-7595","position":12,"is_corresponding":false},{"id":108737,"name":"Cassandra N. Spracklen","orcid":"0000-0003-3590-7182","position":13,"is_corresponding":false},{"id":1105552,"name":"Aaron Holman-Vittone","orcid":null,"position":0,"is_corresponding":true}],"reference_count":50,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T01:14:46.760245Z","pmid":"37114530","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}