{"doi":"10.1017/s0954579423000184","title":"Psychopathology as dynamic markers of alcohol initiation across development: A three-year longitudinal examination","abstract":"<jats:title>Abstract</jats:title><jats:p>Sipping, an early form of alcohol initiation, is associated with aspects of psychopathology and personality that reflect long-term risk for harmful alcohol use. In the Adolescent Brain and Cognitive Development cohort (<jats:italic>N</jats:italic> = 11,872), sipping by age 9–10 was concurrently associated with impulsivity, other aspects of externalizing, and prodromal schizophrenia symptoms. Still, these associations were cross-sectional in nature, leaving open the possibility that these features of psychopathology and personality might not reflect long-term risk for alcohol consumption and related harm across development. Here, we attempted to replicate baseline concurrent associations across three waves of data to extend concurrent associations to prospective ones. Most cross-sectional associations replicated across waves, such that impulsivity, other aspects of externalizing, reward sensitivity (e.g., surgency, sensation seeking), and prodromal schizophrenia symptoms were associated with increased odds of having sipped alcohol by the age of 12. Nevertheless, not all concurrent associations replicated prospectively; impulsigenic features did not reflect long-term risk for sipping. Thus, some psychopathology features appeared to reflect stable risk factors, whereas others appeared to reflect state-dependent risk factors. All told, sipping might not reflect long-term risk for harmful alcohol use, and the nature of sipping may change across development.</jats:p>","journal":"Development and Psychopathology","year":2024,"id":628699,"datarank":0.40620753016533157,"base_score":2.70805020110221,"endowment":2.70805020110221,"self_citation_contribution":0.40620753016533157,"citation_network_contribution":0.0,"self_endowment_contribution":0.40620753016533157,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":14,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1627863,"name":"Mark I. Doss","orcid":null,"position":1,"is_corresponding":false},{"id":793099,"name":"Donte L. Bernard","orcid":"0000-0002-0511-6657","position":2,"is_corresponding":false},{"id":338698,"name":"Kenneth J. Sher","orcid":"0000-0002-4420-8546","position":3,"is_corresponding":false},{"id":559114,"name":"Ashley L. Watts","orcid":"0000-0002-8210-4748","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Psychopathology as dynamic markers of alcohol initiation across development: A three-year longitudinal examination","abstract":"<jats:title>Abstract</jats:title><jats:p>Sipping, an early form of alcohol initiation, is associated with aspects of psychopathology and personality that reflect long-term risk for harmful alcohol use. In the Adolescent Brain and Cognitive Development cohort (<jats:italic>N</jats:italic> = 11,872), sipping by age 9–10 was concurrently associated with impulsivity, other aspects of externalizing, and prodromal schizophrenia symptoms. Still, these associations were cross-sectional in nature, leaving open the possibility that these features of psychopathology and personality might not reflect long-term risk for alcohol consumption and related harm across development. Here, we attempted to replicate baseline concurrent associations across three waves of data to extend concurrent associations to prospective ones. Most cross-sectional associations replicated across waves, such that impulsivity, other aspects of externalizing, reward sensitivity (e.g., surgency, sensation seeking), and prodromal schizophrenia symptoms were associated with increased odds of having sipped alcohol by the age of 12. Nevertheless, not all concurrent associations replicated prospectively; impulsigenic features did not reflect long-term risk for sipping. Thus, some psychopathology features appeared to reflect stable risk factors, whereas others appeared to reflect state-dependent risk factors. All told, sipping might not reflect long-term risk for harmful alcohol use, and the nature of sipping may change across development.</jats:p>","is_dataset_classified":null,"base_score":2.70805020110221,"endowment":2.70805020110221,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"36939078","pmcid":"PMC10509330","openalex_id":"https://openalex.org/W4327892782","authors":[],"funders":[{"funder_name":"NIDA NIH HHS","grant_id":"U01 DA041025","title":null},{"funder_name":"NIDA NIH HHS","grant_id":"U01 DA041028","title":null},{"funder_name":"NIDA NIH HHS","grant_id":"U01 DA041089","title":null},{"funder_name":"NIDA NIH HHS","grant_id":"U01 DA041093","title":null},{"funder_name":"NIDA NIH HHS","grant_id":"U24 DA041123","title":null},{"funder_name":"NIMHD NIH HHS","grant_id":"K23 MD016168","title":null},{"funder_name":"NIDA NIH HHS","grant_id":"U01 DA041156","title":null},{"funder_name":"NIDA NIH HHS","grant_id":"U01 DA041048","title":null},{"funder_name":"NIDA NIH HHS","grant_id":"U01 DA041106","title":null},{"funder_name":"NIDA NIH HHS","grant_id":"U01 DA041120","title":null},{"funder_name":"NIDA NIH HHS","grant_id":"U01 DA041134","title":null},{"funder_name":"NIDA NIH HHS","grant_id":"U01 DA041022","title":null},{"funder_name":"NIDA NIH HHS","grant_id":"U01 DA041148","title":null},{"funder_name":"NIAAA NIH HHS","grant_id":"K99 AA028306","title":null},{"funder_name":"NIDA NIH HHS","grant_id":"U01 DA041174","title":null}],"total_grants":15,"fwci":2.3919,"citation_percentile":0.89566563,"influential_citations":0,"citation_trend":[{"year":2023,"count":1},{"year":2024,"count":6},{"year":2025,"count":5},{"year":2026,"count":2}],"oa_status":"green","license":"https://www.cambridge.org/core/terms","oa_locations":[{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10509330/pdf/nihms-1870031.pdf","host_type":"repository"},{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10509330/pdf/nihms-1870031.pdf","host_type":"repository"},{"url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0954579423000184","host_type":"publisher"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10509330","host_type":"repository"},{"url":"https://doi.org/10.1017/s0954579423000184","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/36939078","host_type":"repository"}],"fields_of_study":["Substance Abuse Treatment and Outcomes","Gambling Behavior and Treatments","Schizophrenia research and treatment","Humans","Male","Female","Longitudinal Studies","Adolescent","Impulsive Behavior","Child","Cross-Sectional Studies","Risk Factors","Alcohol Drinking","Prodromal Symptoms","Underage Drinking","Schizophrenia","Personality","Adolescent Behavior","Psychopathology"],"mesh_terms":["Underage Drinking","Adolescent","Adolescent Behavior","Alcohol Drinking","Child","Cross-Sectional Studies","Female","Humans","Impulsive Behavior","Longitudinal Studies","Male","Personality","Psychopathology","Risk Factors","Schizophrenia","Prodromal Symptoms"],"keywords":["Impulsivity","Psychopathology","Psychology","Sensation seeking","Clinical psychology","Personality","Odds","Longitudinal study","Psychiatry","Schizophrenia (object-oriented programming)","Harm avoidance","Big Five personality traits","Medicine","Logistic regression","Internal medicine","Alcohol Sipping","Alcohol Involvement","Alcohol Initiation"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-05T14:41:18.876087Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}