{"doi":"10.1017/s0031182000049957","title":"Energy metabolism and its regulation in the adult liver fluke<i>Fasciola hepatica</i>","abstract":"<jats:title>SUMMARY</jats:title><jats:p>The adult liver fluke,<jats:italic>Fasciola hepatica</jats:italic>, inhabits the bile duct of its final host, usually cattle or sheep. The veterinary aspects of infection with<jats:italic>F. hepatica</jats:italic>can represent a major problem and consequently fascioliasis can have serious economic effects. As recently as 1972 the loss in revenue due to liver fluke infestations in the UK was estimated at an incredible £50 million per annum (Coles, 1975). Not only can<jats:italic>F. hepatica</jats:italic>infect cattle and sheep, but also outbreaks of human disease have been reported. The last serious outbreak in Britain was in 1968 when at least 49 cases were identified (Ashton, Boardman, D'Sa, Everall &amp; Houghton, 1970; Hardman, Jones &amp; Davies, 1970).</jats:p>","journal":"Parasitology","year":1986,"id":662549,"datarank":0.4566783656585135,"base_score":3.044522437723423,"endowment":3.044522437723423,"self_citation_contribution":0.4566783656585135,"citation_network_contribution":0.0,"self_endowment_contribution":0.4566783656585135,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":20,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1729658,"name":"G. M. 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The last serious outbreak in Britain was in 1968 when at least 49 cases were identified (Ashton, Boardman, D'Sa, Everall &amp; Houghton, 1970; Hardman, Jones &amp; Davies, 1970).</jats:p>","is_dataset_classified":null,"base_score":3.044522437723423,"endowment":3.044522437723423,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"2944061","pmcid":null,"openalex_id":"https://openalex.org/W2009816122","authors":[],"funders":[],"total_grants":0,"fwci":2.792,"citation_percentile":0.8825431,"influential_citations":0,"citation_trend":[{"year":2013,"count":1},{"year":2018,"count":1},{"year":2019,"count":1},{"year":2025,"count":2},{"year":2026,"count":1}],"oa_status":"closed","license":"https://www.cambridge.org/core/terms","oa_locations":[{"url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0031182000049957","host_type":"publisher"},{"url":"https://doi.org/10.1017/s0031182000049957","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/2944061","host_type":"repository"}],"fields_of_study":["Helminth infection and control","Coccidia and coccidiosis research","Parasite Biology and Host Interactions","Adenosine Triphosphate","Anaerobiosis","Animals","Carbohydrate Metabolism","Energy Metabolism","Fasciola hepatica","Fructosediphosphates","Fumarate Hydratase","Glycolysis","Hexokinase","Hormones","Malates","Oxidation-Reduction","Oxygen Consumption","Phosphoenolpyruvate","Phosphoenolpyruvate Carboxykinase (GTP)","Phosphofructokinase-1","Phosphorylases","Pyruvate Kinase","Pyruvates","Succinate Dehydrogenase"],"mesh_terms":["Adenosine Triphosphate","Anaerobiosis","Animals","Energy Metabolism","Fasciola hepatica","Fructosediphosphates","Fumarate Hydratase","Phosphorylases","Glycolysis","Hexokinase","Hormones","Malates","Oxidation-Reduction","Oxygen Consumption","Phosphoenolpyruvate","Phosphoenolpyruvate Carboxykinase (GTP)","Phosphofructokinase-1","Pyruvate Kinase","Pyruvates","Succinate Dehydrogenase","Carbohydrate Metabolism"],"keywords":["Fasciola hepatica","Hepatica","Liver fluke","Biology","Outbreak","Veterinary medicine","Fasciola","Helminths","Zoology","Virology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-12T15:46:35.638979Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}