{"doi":"10.1017/s0016672300034807","title":"Dosage compensation and sex-chromatin in non-mammals","abstract":"<jats:p>1. Inactivation of one X chromosome in somatic cells of female mammals is a form of dosage compensation of sex-linked genes, but the mechanism is entirely different from that operating in<jats:italic>Drosophila</jats:italic>. The latter is designated as dosage compensation<jats:italic>sensu strictu</jats:italic>.</jats:p><jats:p>2. There is no dosage compensation of barred,<jats:italic>sex-linked dilution</jats:italic>or<jats:italic>slow-feathering</jats:italic>in domestic fowls, of<jats:italic>almond</jats:italic>or<jats:italic>faded</jats:italic>in pigeons, or of<jats:italic>cinnamon</jats:italic>in canaries. Among Lepidoptera the same is true of<jats:italic>sex-linked melanism</jats:italic>in<jats:italic>Lymantria monacha</jats:italic>and of a locus controlling haemolymph colour in<jats:italic>Choritoneura</jats:italic>spp. There is no positive evidence that dosage compensation occurs outside Drosophila and mammals.</jats:p><jats:p>3. Sex-chromatin in female birds (heterogametic) has been reported by several authors; the genetical evidence is against the possibility that this represents (as in mammals) an inactivated X chromosome. Sex-chromatin in the heterogametic sex also occurs in some (not all) Lepidoptera and Heteroptera; in Heteroptera it usually represents a heteropyknotic Y chromosome.</jats:p><jats:p>4. Some complications in Muller's theory of dosage compensation<jats:italic>sensu strictu</jats:italic>are discussed. Not all ‘compensatory modifiers’ are necessarily sex-linked.</jats:p><jats:p>5. The problem of dosage compensation in species with impaternate males is discussed;<jats:italic>fused</jats:italic>in<jats:italic>Habrobracon</jats:italic>is not compensated.</jats:p>","journal":"Genetical Research","year":1964,"id":36943,"datarank":7.110718283492717,"base_score":4.174387269895637,"endowment":4.174387269895637,"self_citation_contribution":0.6261580904843456,"citation_network_contribution":6.484560193008371,"self_endowment_contribution":0.6261580904843456,"citer_contribution":6.484560193008371,"corpus_percentile":null,"corpus_rank":null,"citation_count":64,"citer_count":64,"citers_with_citation_signal":59,"citers_with_endowment":59,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":186121,"name":"A. G. 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