{"doi":"10.1017/ice.2021.518","title":"Occupational risk factors for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection among healthcare personnel: A 6-month prospective analysis of the COVID-19 Prevention in Emory Healthcare Personnel (COPE) Study","abstract":"OBJECTIVES: To determine the incidence of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection among healthcare personnel (HCP) and to assess occupational risks for SARS-CoV-2 infection. DESIGN: Prospective cohort of healthcare personnel (HCP) followed for 6 months from May through December 2020. SETTING: Large academic healthcare system including 4 hospitals and affiliated clinics in Atlanta, Georgia. PARTICIPANTS: HCP, including those with and without direct patient-care activities, working during the coronavirus disease 2019 (COVID-19) pandemic. METHODS: Incident SARS-CoV-2 infections were determined through serologic testing for SARS-CoV-2 IgG at enrollment, at 3 months, and at 6 months. HCP completed monthly surveys regarding occupational activities. Multivariable logistic regression was used to identify occupational factors that increased the risk of SARS-CoV-2 infection. RESULTS: Of the 304 evaluable HCP that were seronegative at enrollment, 26 (9%) seroconverted for SARS-CoV-2 IgG by 6 months. Overall, 219 participants (73%) self-identified as White race, 119 (40%) were nurses, and 121 (40%) worked on inpatient medical-surgical floors. In a multivariable analysis, HCP who identified as Black race were more likely to seroconvert than HCP who identified as White (odds ratio, 4.5; 95% confidence interval, 1.3-14.2). Increased risk for SARS-CoV-2 infection was not identified for any occupational activity, including spending >50% of a typical shift at a patient's bedside, working in a COVID-19 unit, or performing or being present for aerosol-generating procedures (AGPs). CONCLUSIONS: In our study cohort of HCP working in an academic healthcare system, <10% had evidence of SARS-CoV-2 infection over 6 months. No specific occupational activities were identified as increasing risk for SARS-CoV-2 infection.","journal":"Infection Control and Hospital Epidemiology","year":2022,"id":272467,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":11,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.6481,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":422634,"name":"Carly Adams","orcid":"0000-0002-9220-7169","position":1,"is_corresponding":false},{"id":485173,"name":"William Dube","orcid":"0000-0003-1286-4087","position":2,"is_corresponding":false},{"id":731184,"name":"Teresa Smith","orcid":"0000-0002-1792-2664","position":3,"is_corresponding":false},{"id":237966,"name":"Amy C Sherman","orcid":"0000-0002-6075-3990","position":4,"is_corresponding":false},{"id":731861,"name":"Neena Edupuganti","orcid":null,"position":5,"is_corresponding":false},{"id":789204,"name":"Minerva Mendez","orcid":null,"position":6,"is_corresponding":false},{"id":731185,"name":"Nora Chea","orcid":"0000-0002-5195-2277","position":7,"is_corresponding":false},{"id":271475,"name":"Shelley S. Magill","orcid":"0000-0003-4748-1000","position":8,"is_corresponding":false},{"id":731862,"name":"Daniel Espinoza","orcid":null,"position":9,"is_corresponding":false},{"id":731863,"name":"Yerun Zhu","orcid":null,"position":10,"is_corresponding":false},{"id":218089,"name":"Varun K. Phadke","orcid":"0000-0002-0318-4939","position":11,"is_corresponding":false},{"id":106174,"name":"Srilatha Edupuganti","orcid":"0000-0001-6566-9969","position":12,"is_corresponding":false},{"id":485902,"name":"James P. Steinberg","orcid":null,"position":13,"is_corresponding":false},{"id":340413,"name":"Benjamin A. Lopman","orcid":"0000-0002-9238-0068","position":14,"is_corresponding":false},{"id":232744,"name":"Jesse T. Jacob","orcid":"0000-0001-9811-6260","position":15,"is_corresponding":false},{"id":271489,"name":"Scott K. Fridkin","orcid":"0000-0003-4892-693X","position":16,"is_corresponding":false},{"id":237968,"name":"Matthew H. 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