{"doi":"10.1017/ice.2019.303","title":"Pathogens causing central-line–associated bloodstream infections in acute-care hospitals—United States, 2011–2017","abstract":"OBJECTIVE: To describe pathogen distribution and rates for central-line-associated bloodstream infections (CLABSIs) from different acute-care locations during 2011-2017 to inform prevention efforts. METHODS: CLABSI data from the Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN) were analyzed. Percentages and pooled mean incidence density rates were calculated for a variety of pathogens and stratified by acute-care location groups (adult intensive care units [ICUs], pediatric ICUs [PICUs], adult wards, pediatric wards, and oncology wards). RESULTS: From 2011 to 2017, 136,264 CLABSIs were reported to the NHSN by adult and pediatric acute-care locations; adult ICUs and wards reported the most CLABSIs: 59,461 (44%) and 40,763 (30%), respectively. In 2017, the most common pathogens were Candida spp/yeast in adult ICUs (27%) and Enterobacteriaceae in adult wards, pediatric wards, oncology wards, and PICUs (23%-31%). Most pathogen-specific CLABSI rates decreased over time, excepting Candida spp/yeast in adult ICUs and Enterobacteriaceae in oncology wards, which increased, and Staphylococcus aureus rates in pediatric locations, which did not change. CONCLUSIONS: The pathogens associated with CLABSIs differ across acute-care location groups. Learning how pathogen-targeted prevention efforts could augment current prevention strategies, such as strategies aimed at preventing Candida spp/yeast and Enterobacteriaceae CLABSIs, might further reduce national rates.","journal":"Infection Control and Hospital Epidemiology","year":2020,"id":54987,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":97,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.5409,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":283919,"name":"Lucy Fike","orcid":"0000-0002-8736-9286","position":1,"is_corresponding":false},{"id":73920,"name":"Margaret A. Dudeck","orcid":"0000-0001-8537-1940","position":2,"is_corresponding":false},{"id":283920,"name":"Katherine Allen‐Bridson","orcid":"0000-0002-6578-0832","position":3,"is_corresponding":false},{"id":271485,"name":"Jonathan R. Edwards","orcid":"0000-0002-1461-8499","position":4,"is_corresponding":false},{"id":286766,"name":"Chris Edens","orcid":null,"position":5,"is_corresponding":false},{"id":286767,"name":"Ronda L. Sinkowitz‐Cochran","orcid":null,"position":6,"is_corresponding":false},{"id":286768,"name":"Krista Powell","orcid":null,"position":7,"is_corresponding":false},{"id":283921,"name":"David T. Kuhar","orcid":"0000-0003-4208-0101","position":8,"is_corresponding":false},{"id":283918,"name":"Shannon Novosad","orcid":"0000-0002-2433-8896","position":0,"is_corresponding":true}],"reference_count":29,"raw_metadata":null,"created_at":"2026-07-18T21:04:59.506324Z","pmid":"31915083","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}