{"doi":"10.1017/cts.2025.77","title":"Patient-generated health data: Impact on promoting patient-centered point of care tobacco treatment in patients with cancer","abstract":"Abstract Introduction: Guideline-based tobacco treatment is infrequently offered. Electronic health record-enabled patient-generated health data (PGHD) has the potential to increase patient treatment engagement and satisfaction. Methods: We evaluated outcomes of a strategy to enable PGHD in a medical oncology clinic from July 1, 2021 to December 31, 2022. Among 12,777 patients, 82.1% received a tobacco screener about use and interest in treatment as part of eCheck-in via the patient portal. Results: We attained a broad reach (82.1%) and moderate response rate (30.9%) for this low-burden PGHD strategy. Patients reporting current smoking ( n = 240) expressed interest in smoking cessation medication (47.9%) and counseling (35.8%). As a result of patient requests via PGHD, most tobacco treatment requests by patients were addressed by their providers (40.6–80.3%). Among patients with active smoking, those who received/answered the screener ( n = 309 ) were more likely to receive tobacco treatment compared with usual care patients who did not have the patient portal ( n = 323) (OR = 2.72, 95% CI = 1.93–3.82, P < 0.0001) using propensity scores to adjust for the effect of age, sex, race, insurance, and comorbidity. Patients who received yet ignored the screener ( n = 1024) compared with usual care were also more likely to receive tobacco treatment, but to a lesser extent (OR = 2.20, 95% CI = 1.68–2.86, P < 0.0001). We mapped observed and potential benefits to the Translational Science Benefits Model (TSBM). Discussion: PGHD via patient portal appears to be a feasible, acceptable, scalable, and cost-effective approach to promote patient-centered care and tobacco treatment in cancer patients. Importantly, the PGHD approach serves as a real world example of cancer prevention leveraging the TSBM.","journal":"Journal of Clinical and Translational Science","year":2025,"id":543956,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.8063,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":461042,"name":"Timothy B. Baker","orcid":"0000-0002-6179-6386","position":1,"is_corresponding":false},{"id":753821,"name":"Jingling Chen","orcid":"0000-0001-7384-5299","position":2,"is_corresponding":false},{"id":478317,"name":"Nina Smock","orcid":null,"position":3,"is_corresponding":false},{"id":1434243,"name":"Nicholas B. Griffith","orcid":null,"position":4,"is_corresponding":false},{"id":13501,"name":"Ramaswamy Govindan","orcid":"0000-0002-6964-9612","position":5,"is_corresponding":false},{"id":754298,"name":"Paula B. Goldberg","orcid":null,"position":6,"is_corresponding":false},{"id":1434244,"name":"Jodi Thole","orcid":null,"position":7,"is_corresponding":false},{"id":1434245,"name":"Kristin Daly","orcid":null,"position":8,"is_corresponding":false},{"id":1434246,"name":"James Reddy","orcid":null,"position":9,"is_corresponding":false},{"id":455297,"name":"Alex T. Ramsey","orcid":"0000-0002-3471-3725","position":10,"is_corresponding":false},{"id":14720,"name":"Laura J. Bierut","orcid":"0000-0002-9952-4810","position":11,"is_corresponding":false},{"id":434061,"name":"Aimee S. James","orcid":"0000-0002-1411-9307","position":12,"is_corresponding":false},{"id":414466,"name":"Robert A. Schnoll","orcid":"0000-0002-4089-856X","position":13,"is_corresponding":false},{"id":251581,"name":"Ross C. Brownson","orcid":"0000-0003-4260-2205","position":14,"is_corresponding":false},{"id":320929,"name":"Li‐Shiun Chen","orcid":"0000-0001-6762-5054","position":15,"is_corresponding":false},{"id":493693,"name":"Jessica Liu","orcid":"0000-0002-8455-0127","position":0,"is_corresponding":true}],"reference_count":5,"raw_metadata":null,"created_at":"2026-07-19T02:53:08.338070Z","pmid":"40529004","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}