{"doi":"10.1017/cts.2020.561","title":"I-Corps@NCATS trains clinical and translational science teams to accelerate translation of research innovations into practice","abstract":"Abstract Introduction: A key barrier to translation of biomedical research discoveries is a lack of understanding among scientists regarding the complexity and process of implementation. To address this challenge, the National Science Foundation’s Innovation Corps™ (I-Corps™) program trains researchers in entrepreneurship. We report results from the implementation of an I-Corps™ training program aimed at biomedical scientists from institutions funded by the National Center for Advancing Translational Sciences (NCATS). Methods: National/regional instructors delivered 5-week I-Corps@NCATS short courses to 62 teams (150 individuals) across six institutions. Content included customer discovery, value proposition, and validating needs. Teams interviewed real-life customers and presented the value of innovations for specific end-users weekly, culminating in a “Finale” featuring their refined business thesis and business model canvas. Methodology was developed to evaluate the newly adapted program. National mixed-methods evaluation assessed program implementation, reach, effectiveness using observations of training delivery and surveys at Finale ( n = 55 teams), and 3–12 months post-training ( n = 34 teams). Results: Innovations related to medical devices (33%), drugs/biologics (20%), software applications (16%), and diagnostics (8%). An average of 24 interviews was conducted. Teams reported increased readiness for commercialization over time (83%, 9 months; 14%, 3 months). Thirty-nine percent met with institutional technology transfer to pursue licensing/patents and 24% pursued venture capital/investor funding following the short courses. Conclusions: I-Corps@NCATS training provided the NCATS teams a rigorous and repeatable process to aid development of a business model based on customer needs. Outcomes of this pilot program support the expansion of I-Corps™ training to biomedical scientists for accelerating research translation.","journal":"Journal of Clinical and Translational Science","year":2020,"id":70167,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":20,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9553,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":372796,"name":"Julie Rainwater","orcid":null,"position":1,"is_corresponding":false},{"id":372797,"name":"Stacey Neves","orcid":null,"position":2,"is_corresponding":false},{"id":371417,"name":"Pamela Bhatti","orcid":"0000-0002-1558-9597","position":3,"is_corresponding":false},{"id":372798,"name":"Bruce A. Conway","orcid":null,"position":4,"is_corresponding":false},{"id":371418,"name":"Nathaniel Hafer","orcid":"0000-0002-0164-5092","position":5,"is_corresponding":false},{"id":372799,"name":"Kevin Harter","orcid":null,"position":6,"is_corresponding":false},{"id":313854,"name":"Nicholas J. Kenyon","orcid":"0000-0001-8839-4400","position":7,"is_corresponding":false},{"id":371419,"name":"Margaret McManus","orcid":"0000-0002-9707-4991","position":8,"is_corresponding":false},{"id":371420,"name":"Demetria M. McNeal","orcid":"0000-0002-7415-8631","position":9,"is_corresponding":false},{"id":371421,"name":"Elaine H. Morrato","orcid":"0000-0001-6105-7826","position":10,"is_corresponding":false},{"id":371422,"name":"Suhrud M. Rajguru","orcid":"0000-0001-5953-8516","position":11,"is_corresponding":false},{"id":371423,"name":"Molly Wasko","orcid":"0000-0002-1982-1824","position":12,"is_corresponding":false},{"id":371416,"name":"Kathryn Nearing","orcid":"0000-0003-1922-7320","position":0,"is_corresponding":true}],"reference_count":7,"raw_metadata":null,"created_at":"2026-07-18T21:43:11.119231Z","pmid":"33948285","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}