{"doi":"10.1016/j.ypmed.2011.06.009","title":"Digital mammography screening: Weighing reduced mortality against increased overdiagnosis","abstract":null,"journal":"Preventive Medicine","year":2011,"id":616419,"datarank":0.6038027536102726,"base_score":4.02535169073515,"endowment":4.02535169073515,"self_citation_contribution":0.6038027536102726,"citation_network_contribution":0.0,"self_endowment_contribution":0.6038027536102726,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":55,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1589230,"name":"Jacques Fracheboud","orcid":null,"position":1,"is_corresponding":false},{"id":385725,"name":"Eveline A.M. Heijnsdijk","orcid":"0000-0002-4890-6069","position":2,"is_corresponding":false},{"id":1589231,"name":"Gerard den Heeten","orcid":null,"position":3,"is_corresponding":false},{"id":1589233,"name":"André L.M. Verbeek","orcid":null,"position":4,"is_corresponding":false},{"id":1589236,"name":"Mireille J.M. Broeders","orcid":null,"position":5,"is_corresponding":false},{"id":1517668,"name":"Gerrit Draisma","orcid":null,"position":6,"is_corresponding":false},{"id":305675,"name":"Harry J. de Koning","orcid":"0000-0003-4682-3646","position":7,"is_corresponding":false},{"id":1589229,"name":"Rianne de Gelder","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Digital mammography screening: Weighing reduced mortality against increased overdiagnosis","abstract":"<h4>Objective</h4>Digital mammography has been shown to increase the detection of ductal carcinoma in situ (DCIS) compared to screen-film mammography. The benefits and risks of such an increase were assessed.<h4>Methods</h4>Breast cancer detection rates were compared between 502,574 screen-film and 83,976 digital mammograms performed between 2004 and 2006 among Dutch screening participants. The detection rates were then modeled using a baseline model and two extreme models that respectively assumed a high rate of progression and no progression of preclinical DCIS to invasive cancer. With these models, breast cancer mortality and overdiagnosis were predicted.<h4>Results</h4>The DCIS detection rate was significantly higher at digital mammography (1.2 per 1000 mammograms (95% C.I. 1.0-1.5)) than at screen-film mammography (0.7 per 1000 mammograms (95% C.I. 0.6-0.7)). Consequently, 287 (range progressive- non progressive model: 1-598) extra breast cancer deaths per 1,000,000 women (a 4.4% increase) were predicted to be prevented. An extra 401 (range: 165-2271) cancers would be overdiagnosed (a 21% increase).<h4>Conclusion</h4>Modeling predicted that digital mammography screening would further reduce breast cancer mortality by 4.4%, at a 21% increased overdiagnosis rate. The consequences of digital screening, however, are sensitive to underlying assumptions on the natural history of DCIS.","is_dataset_classified":null,"base_score":4.02535169073515,"endowment":4.02535169073515,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"21718717","pmcid":null,"openalex_id":"https://openalex.org/W2112087079","authors":[],"funders":[],"total_grants":0,"fwci":3.8413,"citation_percentile":0.93626279,"influential_citations":0,"citation_trend":[{"year":2012,"count":3},{"year":2013,"count":7},{"year":2014,"count":5},{"year":2015,"count":6},{"year":2016,"count":9},{"year":2017,"count":4},{"year":2018,"count":3},{"year":2019,"count":1},{"year":2020,"count":5},{"year":2022,"count":2},{"year":2023,"count":1},{"year":2024,"count":4},{"year":2025,"count":3}],"oa_status":"closed","license":"https://www.elsevier.com/tdm/userlicense/1.0/","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S0091743511002350?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0091743511002350?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.ypmed.2011.06.009","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/21718717","host_type":"repository"},{"url":"https://pure.eur.nl/en/publications/7fe3a753-d80e-46b2-b3c8-65f420cb58cc","host_type":"repository"},{"url":"http://hdl.handle.net/1765/33305","host_type":"repository"},{"url":"https://hdl.handle.net/2066/97825","host_type":"repository"},{"url":"http://hdl.handle.net/2066/97825","host_type":"repository"}],"fields_of_study":["Digital Radiography and Breast Imaging","AI in cancer detection","Global Cancer Incidence and Screening","Aged","Breast Neoplasms","Carcinoma, Intraductal, Noninfiltrating","Confidence Intervals","Diagnostic Errors","Disease Progression","Early Detection of Cancer","Female","Humans","Incidence","Mammography","Middle Aged","Netherlands","Risk Assessment"],"mesh_terms":["Aged","Breast Neoplasms","Carcinoma, Intraductal, Noninfiltrating","Diagnostic Errors","Female","Humans","Mammography","Middle Aged","Netherlands","Incidence","Confidence Intervals","Disease Progression","Risk Assessment","Early Detection of Cancer"],"keywords":["Overdiagnosis","Medicine","Mammography","Breast cancer","Digital mammography","Breast cancer screening","Ductal carcinoma","Cancer","Internal medicine","Oncology","Radiology","Gynecology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-02T22:50:17.416273Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}