{"doi":"10.1016/j.xpro.2024.102949","title":"Protocol for phage matching, treatment, and monitoring for compassionate bacteriophage use in non-resolving infections","abstract":null,"journal":"STAR Protocols","year":2024,"id":651295,"datarank":0.38474240361923057,"base_score":2.5649493574615367,"endowment":2.5649493574615367,"self_citation_contribution":0.38474240361923057,"citation_network_contribution":0.0,"self_endowment_contribution":0.38474240361923057,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":12,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1028441,"name":"Ortal Yerushalmy","orcid":"0000-0002-8994-3114","position":1,"is_corresponding":false},{"id":1029036,"name":"Ron Braunstein","orcid":null,"position":2,"is_corresponding":false},{"id":1698504,"name":"Sivan Alkalay-Oren","orcid":null,"position":3,"is_corresponding":false},{"id":1028442,"name":"Amit Rimon","orcid":"0000-0002-1749-4786","position":4,"is_corresponding":false},{"id":1028443,"name":"Daniel Gelman","orcid":"0009-0007-3280-722X","position":5,"is_corresponding":false},{"id":1698505,"name":"Shunit Coppenhagen-Glazer","orcid":null,"position":6,"is_corresponding":false},{"id":758536,"name":"Ronen Hazan","orcid":"0000-0001-9967-730X","position":7,"is_corresponding":false},{"id":1028440,"name":"Ran Nir‐Paz","orcid":"0000-0002-1567-2550","position":8,"is_corresponding":false},{"id":1028439,"name":"Hadil Onallah","orcid":"0000-0002-8420-6035","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Protocol for phage matching, treatment, and monitoring for compassionate bacteriophage use in non-resolving infections","abstract":"Phage therapy has re-emerged as a promising treatment for non-resolving infections. Given the lack of approved phage treatments, there is a need to establish a compassionate use pipeline. Here, we present a protocol for phage matching, treatment, and monitoring for compassionate bacteriophage use in non-resolving infections. We describe steps for consultation and request implementation, evaluating and comparing different aspects of phage activity, and phage production. We then detail procedures for multidisciplinary meetings, ethics approvals, phage therapy, and follow-up. For complete details on the use and execution of this protocol, please refer to Onallah et al.1,2","is_dataset_classified":null,"base_score":2.5649493574615367,"endowment":2.5649493574615367,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"38691464","pmcid":null,"openalex_id":"https://openalex.org/W4396503128","authors":[],"funders":[{"funder_name":"Israel Science Foundation","grant_id":"ISF_1349 /20","title":null},{"funder_name":"Rosetrees Trust","grant_id":"A2232","title":null},{"funder_name":"United States Israel Binational Science Foundation","grant_id":"2017123","title":null},{"funder_name":"JPIAMR","grant_id":"3-18737","title":null}],"total_grants":4,"fwci":3.9842,"citation_percentile":0.93431321,"influential_citations":0,"citation_trend":[{"year":2024,"count":2},{"year":2025,"count":6},{"year":2026,"count":4}],"oa_status":"gold","license":"cc-by-nc-nd","oa_locations":[{"url":"https://doi.org/10.1016/j.xpro.2024.102949","host_type":"journal"},{"url":"https://doi.org/10.1016/j.xpro.2024.102949","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S266616672400114X?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S266616672400114X?httpAccept=text/plain","host_type":"publisher"},{"url":"https://pubmed.ncbi.nlm.nih.gov/38691464","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11070627","host_type":"repository"},{"url":"https://doaj.org/article/bb0ce8ecb8074e8fb80592aefdda5cc5","host_type":"repository"},{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11070627/pdf/main.pdf","host_type":"repository"}],"fields_of_study":["Bacteriophages and microbial interactions","Viral gastroenteritis research and epidemiology","Viral Infections and Outbreaks Research"],"mesh_terms":["Phage Therapy","Bacterial Infections","Bacteriophages","Humans","Compassionate Use Trials"],"keywords":["Phage therapy","Bacteriophage","Compassionate Use","Protocol (science)","Medicine","Matching (statistics)","Computer science","Computational biology","Virology","Biology","Genetics","Clinical trial","Alternative medicine","Internal medicine","Gene","Pathology"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-10T07:16:11.772881Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}