{"doi":"10.1016/j.xpro.2020.100056","title":"Patient-Derived Tumor Organoid Rings for Histologic Characterization and High-Throughput Screening","abstract":"Tumor organoids are promising tools for cancer biology investigations and preclinical drug screenings because they are often representative of the histology and drug responses of patients. Here, we introduce a facile protocol to overcome technical limitations by generating patient-derived tumor organoids using a simplified ring-like geometry. This facilitates media exchange and drug treatment for histopathology characterization and automated high-throughput drug screenings. For complete details on the use and execution of this protocol, please refer to Phan et al. (2019).","journal":"STAR Protocols","year":2020,"id":64017,"datarank":0.9973898412343147,"base_score":3.713572066704308,"endowment":3.713572066704308,"self_citation_contribution":0.5570358100056463,"citation_network_contribution":0.4403540312286685,"self_endowment_contribution":0.5570358100056463,"citer_contribution":0.4403540312286685,"corpus_percentile":null,"corpus_rank":null,"citation_count":40,"citer_count":24,"citers_with_citation_signal":18,"citers_with_endowment":18,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9454,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":338846,"name":"Alice Soragni","orcid":"0000-0002-6634-2885","position":1,"is_corresponding":false},{"id":338845,"name":"Huyen Thi Lam Nguyen","orcid":"0000-0001-9309-1025","position":0,"is_corresponding":true}],"reference_count":1,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-18T21:12:32.635050Z","pmid":"33043307","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}