{"doi":"10.1016/j.xops.2022.100155","title":"“Complement-ary” Therapies for Age-Related Macular Degeneration","abstract":"Although anti-VEGF agents have transformed our ability to treat patients with advanced exudative age-related macular degeneration (AMD), there are currently no approved treatments to slow photoreceptor and retinal pigment epithelium degeneration, termed “geographic atrophy” (GA), in patients with advanced nonexudative AMD.1 Based on preclinical and human studies suggesting that complement dysregulation may contribute to AMD pathogenesis,2 significant efforts have been directed toward using complement modulation to slow GA.","journal":"Ophthalmology Science","year":2022,"id":293632,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9524,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":328045,"name":"Rajendra S. Apte","orcid":"0000-0003-2281-2336","position":1,"is_corresponding":false},{"id":382962,"name":"Jonathan B. Lin","orcid":"0000-0002-2792-7821","position":0,"is_corresponding":true}],"reference_count":5,"raw_metadata":null,"created_at":"2026-07-19T00:30:53.818562Z","pmid":"36249691","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}