{"doi":"10.1016/j.xjtc.2023.02.005","title":"New operations for truncus arteriosus repair using partial heart transplantation: Exploring the surgical design space with 3-dimensional printed heart models","abstract":"Central MessageThree-dimensional printed heart models are used to contribute new operations for truncus arteriosus repair using partial heart transplantation. Three-dimensional printed heart models are used to contribute new operations for truncus arteriosus repair using partial heart transplantation. Heart valve replacement has poor outcomes in infants because state-of-the-art homografts do not grow or self-repair. For homograft replacement of semilunar valves in the systemic position, the in-hospital mortality is 40%1Woods R.K. Pasquali S.K. Jacobs M.L. Austin E.H. Jacobs J.P. Krolikowski M. et al.Aortic valve replacement in neonates and infants: an analysis of the society of thoracic surgeons congenital heart surgery database.J Thorac Cardiovasc Surg. 2012; 144: 1084-1089Abstract Full Text Full Text PDF PubMed Scopus (48) Google Scholar and structural deterioration occurs within months. In the pulmonary position, structural deterioration mandates replacement after an average of 5 years.2Wells W.J. Arroyo Jr., H. Bremner R.M. Wood J. Starnes V.A. Homograft conduit failure in infants is not due to somatic outgrowth.J Thorac Cardiovasc Surg. 2002; 124: 88-96Abstract Full Text Full Text PDF PubMed Scopus (133) Google Scholar For homograft replacement of truncal valves,3Sierra J. Beghetti M. Kalangos A. Truncus arteriosus repair with double aortic homograft.J Card Surg. 2004; 19: 252-253Crossref PubMed Scopus (6) Google Scholar the infant mortality is 50% to 75%.4McElhinney D.B. Reddy V.M. Rajasinghe H.A. Mora B.N. Silverman N.H. Hanley F.L. Trends in the management of truncal valve insufficiency.Ann Thorac Surg. 1998; 65: 517-524Abstract Full Text Full Text PDF PubMed Scopus (62) Google Scholar, 5Russell H.M. Pasquali S.K. Jacobs J.P. Jacobs M.L. O’Brien S.M. Mavroudis C. et al.Outcomes of repair of common arterial trunk with truncal valve surgery: a review of the society of thoracic surgeons congenital heart surgery database.Ann Thorac Surg. 2012; 93 (discussion 169): 164-169Abstract Full Text Full Text PDF PubMed Scopus (96) Google Scholar, 6Elkins R.C. Steinberg J.B. Razook J.D. Ward K.E. Overholt E.D. Thompson Jr., W.M. et al.Correction of truncus arteriosus with truncal valvar stenosis or insufficiency using two homografts.Ann Thorac Surg. 1990; 50: 728-733Abstract Full Text PDF PubMed Scopus (26) Google Scholar, 7Henaine R. Azarnoush K. Belli E. Capderou A. Roussin R. Planché C. et al.Fate of the truncal valve in truncus arteriosus.Ann Thorac Surg. 2008; 85: 172-178Abstract Full Text Full Text PDF PubMed Scopus (62) Google Scholar Therefore, there is an urgent clinical need for growing and self-repairing heart valve implants. We developed a new approach for delivering growing and self-repairing heart valve implants that is based on transplantation. This approach is called “partial heart transplantation” because only the part of the heart containing the heart valve is transplanted. The rationale for partial heart transplantation is that neonates with orthotopic heart transplants reach adult size without the need for reintervention8Lin Y. Davis T.J. Zorrilla-Vaca A. Wojcik B.M. Miyamoto S.D. Everitt M.D. et al.Neonatal heart transplant outcomes: a single institutional experience.J Thorac Cardiovasc Surg. 2021; 162: 1361-1368Abstract Full Text Full Text PDF PubMed Scopus (8) Google Scholar because transplanted hearts grow9Bernstein D. Kolla S. Miner M. Pitlick P. Griffin M. Starnes V. et al.Cardiac growth after pediatric heart transplantation.Circulation. 1992; 85: 1433-1439Crossref PubMed Scopus (32) Google Scholar and failure of the transplanted semilunar valves is exceedingly rare.10Valente M. Faggian G. Billingham M.E. Talenti E. Calabrese F. Casula R. et al.The aortic valve after heart transplantation.Ann Thorac Surg. 1995; 60: S135-S140Abstract Full Text PDF PubMed Scopus (31) Google Scholar, 11Goekler J. Zuckermann A. Osorio E. Brkic F.F. Uyanik-Uenal K. Laufer G. et al.Cardiac surgery after heart transplantation: ele","journal":"JTCVS Techniques","year":2023,"id":356949,"datarank":0.42498200160843247,"base_score":2.833213344056216,"endowment":2.833213344056216,"self_citation_contribution":0.42498200160843247,"citation_network_contribution":0.0,"self_endowment_contribution":0.42498200160843247,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":16,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.953,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":955387,"name":"Lillian Kang","orcid":null,"position":1,"is_corresponding":false},{"id":1106459,"name":"Kaila Hayden","orcid":null,"position":2,"is_corresponding":false},{"id":786887,"name":"Nicholas D. 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