{"doi":"10.1016/j.xjon.2022.02.017","title":"Treating lower extremity malperfusion syndrome in acute type A aortic dissection with endovascular revascularization followed by delayed aortic repair","abstract":"Objective: To assess the outcomes of emergency revascularization with endovascular fenestration/stenting followed by delayed open aortic repair in patients with acute type A aortic dissection with lower extremity (LE) malperfusion syndrome (MPS); that is, necrosis and dysfunction of the lower extremity. Methods: From 1996 to 2019, among 760 consecutive acute type A aortic dissection patients 512 patients had no malperfusion syndrome (Non-MPS), whereas 26 patients had LE-MPS with/without renal MPS and underwent endovascular fenestration/stenting, open aortic repair, or both. Patients with coronary, cerebral, mesenteric, and celiac MPS, or managed with thoracic endovascular aortic repair, were excluded (n = 222). All patients with LE-MPS underwent upfront endovascular fenestration/stenting except 1 patient (with signs of rupture) who initially underwent emergency open aortic repair. Results: = .002). Conclusions: In acute type A aortic dissection, LE-MPS was associated with high in-hospital mortality. Emergency revascularization with endovascular fenestration/stenting followed by delayed open aortic repair may be a reasonable approach.","journal":"JTCVS Open","year":2022,"id":268973,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":17,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.7801,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":760882,"name":"Felix Orelaru","orcid":"0000-0001-7591-1835","position":1,"is_corresponding":false},{"id":453687,"name":"Aroma Naeem","orcid":null,"position":2,"is_corresponding":false},{"id":385417,"name":"Xiaoting Wu","orcid":"0000-0001-8011-9324","position":3,"is_corresponding":false},{"id":262056,"name":"Karen M. Kim","orcid":"0000-0002-5641-7572","position":4,"is_corresponding":false},{"id":425830,"name":"David Williams","orcid":"0000-0001-9472-6168","position":5,"is_corresponding":false},{"id":262052,"name":"Shinichi Fukuhara","orcid":"0000-0002-7898-5159","position":6,"is_corresponding":false},{"id":425831,"name":"Himanshu J. Patel","orcid":"0000-0001-7639-2416","position":7,"is_corresponding":false},{"id":243351,"name":"G. Michael Deeb","orcid":"0000-0002-4698-2789","position":8,"is_corresponding":false},{"id":262055,"name":"Bo Yang","orcid":"0000-0002-2158-9155","position":9,"is_corresponding":false},{"id":385416,"name":"Elizabeth L. Norton","orcid":"0000-0003-3678-3820","position":0,"is_corresponding":true}],"reference_count":17,"raw_metadata":null,"created_at":"2026-07-19T00:27:18.142851Z","pmid":"36408122","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}