{"doi":"10.1016/j.xjon.2021.08.005","title":"Rates and types of infections in left ventricular assist device recipients: A scoping review","abstract":"Central MessageThis scoping review found that most studies of infections in LVAD recipients did not utilize standardized infection definitions and did not complete information on infection locations and types.PerspectiveIn this scoping review of 132 studies reporting infections in LVAD recipients, most studies did not use standardized infection definitions and most studies did not report complete demographic information. To advance the scientific rigor of investigations into infections in LVAD recipients, future studies should use standardized definitions and meet minimum reporting guidelines.See Commentaries on Pages 412, 414, and 416. This scoping review found that most studies of infections in LVAD recipients did not utilize standardized infection definitions and did not complete information on infection locations and types. In this scoping review of 132 studies reporting infections in LVAD recipients, most studies did not use standardized infection definitions and most studies did not report complete demographic information. To advance the scientific rigor of investigations into infections in LVAD recipients, future studies should use standardized definitions and meet minimum reporting guidelines. See Commentaries on Pages 412, 414, and 416. Use of left ventricular assist devices (LVADs) has increased over time as the number of patients with end-stage heart failure increases relative to the availability of heart transplant donor organs. Although outcomes in LVAD recipients have improved with advances in technology, infections remain a persistent problem and are the most common adverse event after LVAD implantation.1Molina E.J. Shah P. Kiernan M.S. Cornwell III, W.K. Copeland H. Takeda K. et al.The Society of Thoracic Surgeons Intermacs 2020 annual report.Ann Thorac Surg. 2021; 111: 778-792Abstract Full Text Full Text PDF PubMed Scopus (58) Google Scholar Infections associated with LVAD implantation remain a persistent problem and are the most common adverse event during the first year after LVAD implantation, with only 59% of patients free from major infection at 1 year after implant.1Molina E.J. Shah P. Kiernan M.S. Cornwell III, W.K. Copeland H. Takeda K. et al.The Society of Thoracic Surgeons Intermacs 2020 annual report.Ann Thorac Surg. 2021; 111: 778-792Abstract Full Text Full Text PDF PubMed Scopus (58) Google Scholar Although there are several subtypes of infections in LVAD recipients (eg, driveline infection, bacteremia, pneumonia, and urinary tract infection), all of them have been linked to an increased risk of postimplant complications (eg, rehospitalization, need for device exchange, stroke, or death) as well as associated increased expenditures.2Akhter S.A. Badami A. Murray M. Kohmoto T. Lozonschi L. Osaki S. et al.Hospital readmissions after continuous-flow left ventricular assist device implantation: incidence, causes, and cost analysis.Ann Thorac Surg. 2015; 100: 884-889Abstract Full Text Full Text PDF PubMed Scopus (85) Google Scholar, 3Shah P. Birk S.E. Cooper L.B. Psotka M.A. Kirklin J.K. Barnett S.D. et al.Stroke and death risk in ventricular assist device patients varies by ISHLT infection category: an INTERMACS analysis.J Heart Lung Transplant. 2019; 38: 721-730Abstract Full Text Full Text PDF PubMed Scopus (12) Google Scholar, 4Hannan M.M. Xie R. Cowger J. Schueler S. de By T. Dipchand A.I. et al.Epidemiology of infection in mechanical circulatory support: a global analysis from the ISHLT Mechanically Assisted Circulatory Support Registry.J Heart Lung Transplant. 2019; 38: 364-373Abstract Full Text Full Text PDF PubMed Scopus (37) Google Scholar Despite the burden of infections in LVAD recipients, existing literature investigating this complication are mostly limited to small, single-center observational series. In addition, existing systematic reviews have focused on a limited number of infection subtypes rather than comprehensively studying all infection subtypes among patients receiving contempora","journal":"JTCVS Open","year":2021,"id":177639,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":20,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.956,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":722065,"name":"Supriya Shore","orcid":"0000-0002-5436-6097","position":1,"is_corresponding":false},{"id":495788,"name":"Francis D. 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