{"doi":"10.1016/j.wneu.2018.05.095","title":"Effect of Temporal Neocortical Pathology on Seizure Freeness in Adult Patients with Temporal Lobe Epilepsy","abstract":null,"journal":"World Neurosurgery","year":2018,"id":604077,"datarank":0.31191623125197543,"base_score":2.0794415416798357,"endowment":2.0794415416798357,"self_citation_contribution":0.31191623125197543,"citation_network_contribution":0.0,"self_endowment_contribution":0.31191623125197543,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":7,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1549795,"name":"Merdin Lyutviev Ahmedov","orcid":null,"position":1,"is_corresponding":false},{"id":1549798,"name":"Orkhan Alizada","orcid":null,"position":2,"is_corresponding":false},{"id":1549800,"name":"Seher Naz Yeni","orcid":null,"position":3,"is_corresponding":false},{"id":1549802,"name":"Buge Oz","orcid":null,"position":4,"is_corresponding":false},{"id":1549803,"name":"Taner Tanriverdi","orcid":null,"position":5,"is_corresponding":false},{"id":1549794,"name":"Rahsan Kemerdere","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Effect of Temporal Neocortical Pathology on Seizure Freeness in Adult Patients with Temporal Lobe Epilepsy","abstract":"<h4>Background</h4>Temporal lobe epilepsy (TLE) is the most common form of focal epilepsy. Focal cortical dysplasia is the most common dual pathology found in association with the hippocampal sclerosis. In this study, the effect of dual pathology on freedom from seizure was sought in patients with TLE.<h4>Methods</h4>This study performed a retrospective analysis of patients with TLE who underwent surgery between 2010 and 2017. Histopathologic analysis was performed on patients with and without dual pathology in the temporal neocortex. Seizure outcomes were compared.<h4>Results</h4>A total of 54 patients with TLE were included. The rate of overall favorable seizure outcome was found to be 96.3%. In 53.7%, dual pathology was present in the temporal cortices in addition to the hippocampal sclerosis. Patients without dual pathology showed significantly greater freedom from seizure (P = 0.02).<h4>Conclusions</h4>Patients without dual pathology had a significantly higher seizure-free rate after anterior temporal resection than patients with dual pathology. Resection of the temporal cortex in addition to mesial temporal structures seems to be reasonable for better seizure outcome.","is_dataset_classified":null,"base_score":2.0794415416798357,"endowment":2.0794415416798357,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"29803067","pmcid":null,"openalex_id":"https://openalex.org/W2803502570","authors":[],"funders":[],"total_grants":0,"fwci":0.4523,"citation_percentile":0.62127877,"influential_citations":0,"citation_trend":[{"year":2019,"count":2},{"year":2020,"count":1},{"year":2022,"count":3},{"year":2023,"count":1}],"oa_status":"closed","license":"https://www.elsevier.com/legal/tdmrep-license","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S1878875018310489?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1878875018310489?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.wneu.2018.05.095","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/29803067","host_type":"repository"}],"fields_of_study":["Epilepsy research and treatment","Neuroscience and Neuropharmacology Research","Psychosomatic Disorders and Their Treatments","Adult","Cohort Studies","Epilepsy, Temporal Lobe","Female","Follow-Up Studies","Humans","Male","Malformations of Cortical Development","Neocortex","Retrospective Studies","Seizures","Young Adult"],"mesh_terms":["Adult","Epilepsy, Temporal Lobe","Female","Follow-Up Studies","Humans","Male","Retrospective Studies","Seizures","Cohort Studies","Neocortex","Malformations of Cortical Development","Young Adult"],"keywords":["Temporal lobe","Medicine","Epilepsy","Neocortex","Mesial temporal lobe epilepsy","Neuroscience","Temporal cortex","Pathology","Psychiatry","Psychology","Temporal lobe epilepsy","Focal Cortical Dysplasia","Dual Pathology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Peace, Justice and strong institutions"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-29T23:19:16.869237Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}