{"doi":"10.1016/j.trecan.2025.03.002","title":"Molecular and clinical insights into early-onset endometrial cancer","abstract":null,"journal":"Trends in Cancer","year":2025,"id":630228,"datarank":0.31191623125197543,"base_score":2.0794415416798357,"endowment":2.0794415416798357,"self_citation_contribution":0.31191623125197543,"citation_network_contribution":0.0,"self_endowment_contribution":0.31191623125197543,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":7,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":857997,"name":"Zhe Hu","orcid":"0000-0002-5415-2240","position":1,"is_corresponding":false},{"id":1202467,"name":"Qinlan Li","orcid":"0000-0001-8206-4283","position":2,"is_corresponding":false},{"id":1632554,"name":"Geyan Liu","orcid":null,"position":3,"is_corresponding":false},{"id":406832,"name":"Ana Oaknin","orcid":"0000-0002-3592-7194","position":4,"is_corresponding":false},{"id":1632556,"name":"Juan Francisco Grau Bejar","orcid":null,"position":5,"is_corresponding":false},{"id":13817,"name":"Gordon B. 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The enhanced understanding of the disease's pathophysiology, enabling a more precise differentiation between low-risk and high-risk patients, could facilitate the establishment of risk-stratified treatments that preserve ovarian function and fertility in low-risk EOEC cases. In this review, we delve into the distinctive epidemiological, molecular, and clinical characteristics of EOEC, as well as early noninvasive screening and fertility preservation treatments.","is_dataset_classified":null,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"40133132","pmcid":null,"openalex_id":"https://openalex.org/W4408816908","authors":[],"funders":[{"funder_name":"National Natural Science Foundation of China","grant_id":"82473087","title":null},{"funder_name":"National Natural Science Foundation of China","grant_id":"824B2093","title":null},{"funder_name":"National Key Research and Development Program of China","grant_id":"2022YFC2704300","title":null},{"funder_name":"National Key Research and Development Program of China","grant_id":"2022YFC2704301","title":null}],"total_grants":4,"fwci":6.9649,"citation_percentile":0.96809713,"influential_citations":0,"citation_trend":[{"year":2025,"count":1},{"year":2026,"count":5}],"oa_status":"closed","license":"https://doi.org/10.15223/policy-004","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S2405803325000706?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S2405803325000706?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.trecan.2025.03.002","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/40133132","host_type":"repository"}],"fields_of_study":["Endometrial and Cervical Cancer Treatments","Estrogen and related hormone effects","Endometriosis Research and Treatment","Humans","Endometrial Neoplasms","Female","Age of Onset","Fertility Preservation","Early Detection of Cancer","Incidence","Biomarkers, Tumor","Risk Factors"],"mesh_terms":["Female","Humans","Risk Factors","Biomarkers, Tumor","Incidence","Endometrial Neoplasms","Age of Onset","Early Detection of Cancer","Fertility Preservation"],"keywords":["Endometrial cancer","Cancer","Oncology","Medicine","Internal medicine","Biology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-05T20:42:39.971640Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}