{"doi":"10.1016/j.toxrep.2020.08.027","title":"The role of carbon monoxide and heme oxygenase-1 in COVID-19","abstract":"• Low level carbon monoxide (CO) and heme oxygenase-1 (HO-1) may play a role on the effect of smoking on COVID-19. • CO and HO-1 are anti-inflammatory and cytoprotective and HO-1 is most protective if it is induced before the occurrence of an oxidative insult. • COVID-19 may by itself induce HO-1 and CO which may be potential markers of inflammation or cytokine storm. • Some asymptomatic patients of COVID-19 may have a high baseline level of HO-1 or CO before their COVID-19 infection. • Non-invasive measurement of carboxyhemoglobin using a pulse CO-oximeter may be used to index CO and HO-1 level.","journal":"Toxicology Reports","year":2020,"id":74275,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":11,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9578,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":289035,"name":"Suk‐Tak Chan","orcid":"0000-0001-6627-3173","position":1,"is_corresponding":false},{"id":388678,"name":"Kenneth K. Kwong","orcid":"0000-0001-5056-2173","position":0,"is_corresponding":true}],"reference_count":36,"raw_metadata":null,"created_at":"2026-07-18T21:45:52.171053Z","pmid":"32904637","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}