{"doi":"10.1016/j.tma.2020.08.003","title":"SPOCK, an R based package for high-throughput analysis of growth rate, survival, and chronological lifespan in yeast","abstract":"Plate-reader based methods for high-throughput measurement of growth rate, cellular survival, and chronological lifespan are a compelling addition to the already powerful toolbox of budding yeast Saccharomyces cerevisiae genetics. These methods have overcome many of the limits of traditional yeast biology techniques, but also present a new bottleneck at the point of data-analysis. Herein, we describe SPOCK (Survival Percentage and Outgrowth Collection Kit), an R-based package for the analysis of data created by high-throughput plate reader based methods. This package allows for the determination of chronological lifespan, cellular growth rate, and survival in an efficient, robust, and reproducible fashion.","journal":"Translational Medicine of Aging","year":2020,"id":73296,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":13,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9454,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":386634,"name":"Daniel P. Felker","orcid":null,"position":1,"is_corresponding":false},{"id":386635,"name":"Olivia C. Heath","orcid":null,"position":2,"is_corresponding":false},{"id":385639,"name":"Ryla J. Cantergiani","orcid":"0000-0001-8522-457X","position":3,"is_corresponding":false},{"id":385640,"name":"Christine Robbins","orcid":"0000-0003-1976-9242","position":4,"is_corresponding":false},{"id":385641,"name":"Mary Ann Osley","orcid":"0000-0003-3287-7379","position":5,"is_corresponding":false},{"id":267062,"name":"Mark A. McCormick","orcid":"0000-0002-4916-8280","position":6,"is_corresponding":false},{"id":385638,"name":"Eric M. Small","orcid":"0000-0002-6960-4393","position":0,"is_corresponding":true}],"reference_count":30,"raw_metadata":null,"created_at":"2026-07-18T21:45:32.034078Z","pmid":"33542965","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}