{"doi":"10.1016/j.tim.2021.10.004","title":"Advances in the bacterial organelles for CO2 fixation","abstract":null,"journal":"Trends in Microbiology","year":2022,"id":645443,"datarank":0.7301301675683375,"base_score":4.867534450455582,"endowment":4.867534450455582,"self_citation_contribution":0.7301301675683375,"citation_network_contribution":0.0,"self_endowment_contribution":0.7301301675683375,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":129,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1221953,"name":"Lu‐Ning Liu","orcid":"0000-0002-8884-4819","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Advances in the bacterial organelles for CO2 fixation","abstract":"Carboxysomes are a family of bacterial microcompartments (BMCs), present in all cyanobacteria and some proteobacteria, which encapsulate the primary CO<sub>2</sub>-fixing enzyme, Rubisco, within a virus-like polyhedral protein shell. Carboxysomes provide significantly elevated levels of CO<sub>2</sub> around Rubisco to maximize carboxylation and reduce wasteful photorespiration, thus functioning as the central CO<sub>2</sub>-fixation organelles of bacterial CO<sub>2</sub>-concentration mechanisms. Their intriguing architectural features allow carboxysomes to make a vast contribution to carbon assimilation on a global scale. In this review, we discuss recent research progress that provides new insights into the mechanisms of how carboxysomes are assembled and functionally maintained in bacteria and recent advances in synthetic biology to repurpose the metabolic module in diverse applications.","is_dataset_classified":null,"base_score":4.867534450455582,"endowment":4.867534450455582,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"34802870","pmcid":null,"openalex_id":"https://openalex.org/W3211930719","authors":[],"funders":[{"funder_name":"National Natural Science Foundation of China","grant_id":"32070109","title":null},{"funder_name":"Biotechnology and Biological Sciences Research Council","grant_id":"BB/M024202/1","title":"Biosynthesis, Regulation and Engineering of Bacterial Carbon Fixation Machinery"},{"funder_name":"Biotechnology and Biological Sciences Research Council","grant_id":"BB/R003890/1","title":"Organisation, dynamics and biogenesis of a photosynthetic membrane"},{"funder_name":"Biotechnology and Biological Sciences Research Council","grant_id":"BB/V009729/1","title":"Deciphering the molecular principles of bacterial metabolosome biogenesis"},{"funder_name":"Leverhulme Trust","grant_id":"RPG-2021-286","title":null},{"funder_name":"Royal Society","grant_id":"RGF\\EA\\180233","title":null},{"funder_name":"Royal Society","grant_id":"RGF\\EA\\181061","title":null},{"funder_name":"Royal Society","grant_id":"URF\\R\\180030","title":null},{"funder_name":"Biotechnology and Biological Sciences Research Council","grant_id":"BB/R01390X/1","title":null},{"funder_name":"Biotechnology and Biological Sciences Research Council","grant_id":"BB/T017813/1","title":null}],"total_grants":10,"fwci":5.7015,"citation_percentile":0.97479336,"influential_citations":0,"citation_trend":[{"year":2021,"count":2},{"year":2022,"count":16},{"year":2023,"count":20},{"year":2024,"count":39},{"year":2025,"count":33},{"year":2026,"count":19}],"oa_status":"closed","license":"Elsevier TDM","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S0966842X21002596?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0966842X21002596?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.tim.2021.10.004","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/34802870","host_type":"repository"},{"url":"https://dx.doi.org/10.1016/j.tim.2021.10.004","host_type":""}],"fields_of_study":["Photosynthetic Processes and Mechanisms","Microbial Community Ecology and Physiology","Microbial Metabolic Engineering and Bioproduction","0301 basic medicine","0303 health sciences","03 medical and health sciences","Bacterial Proteins","Carbon Cycle","Carbon Dioxide","Cyanobacteria","Organelles","Ribulose-Bisphosphate Carboxylase"],"mesh_terms":["Cyanobacteria","Bacterial Proteins","Carbon Dioxide","Ribulose-Bisphosphate Carboxylase","Organelles","Carbon Cycle"],"keywords":["RuBisCO","Carbon fixation","Biology","Organelle","Cyanobacteria","Biochemistry","Computational biology","Cell biology","Photosynthesis","Bacteria","Genetics","Self-assembly","Synthetic Biology","Carboxysome","Co(2) Fixation","Bacterial Microcompartment","Co(2)-concentrating Mechanisms","Organelles","Bacterial Proteins","Ribulose-Bisphosphate Carboxylase","Carbon Dioxide","Carbon Cycle"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Responsible consumption and production"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-09T05:43:57.502117Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}