{"doi":"10.1016/j.sipas.2023.100232","title":"Utility of beta-lactam allergy assessment in patients receiving vancomycin for surgical prophylaxis","abstract":"Background: Beta-lactam antibiotics are first-line agents for most patients receiving antimicrobial prophylaxis in surgical procedures. Despite evidence showing low cross-reactivity between penicillins and cephalosporins, patients with beta-lactam allergies commonly receive vancomycin as an alternative to avoid allergic reaction. Methods: Adult patients receiving vancomycin for surgical prophylaxis with a reported beta-lactam allergy at our institution between August 2017 to July 2018 were retrospectively evaluated for potential eligibility for penicillin allergy testing and/or receipt of standard prophylaxis. Results: Among 830 patients who received vancomycin for surgical prophylaxis, 196 reported beta-lactam allergy and were included in the analysis. Approximately 40 % of surgeries were orthopedic. Of patients receiving vancomycin as first-line therapy, 189 (96.4 %) were potentially eligible for beta-lactam prophylaxis. Conclusions: Patients with beta-lactam allergies often qualify for receipt of a first-line antibiotic. An opportunity exists for improved allergy assessment as an antimicrobial stewardship intervention in surgical prophylaxis.","journal":"Surgery in Practice and Science","year":2023,"id":415220,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9613,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1197288,"name":"YoungYoon Ham","orcid":null,"position":1,"is_corresponding":false},{"id":1196984,"name":"Haley K Holmer","orcid":"0000-0003-4198-8708","position":2,"is_corresponding":false},{"id":676968,"name":"Caitlin M. McCracken","orcid":"0000-0003-3234-3860","position":3,"is_corresponding":false},{"id":1026857,"name":"Ellie Sukerman","orcid":"0000-0001-8030-7229","position":4,"is_corresponding":false},{"id":1019483,"name":"James S. Lewis","orcid":"0000-0003-3375-2199","position":5,"is_corresponding":false},{"id":676969,"name":"Jessina C. McGregor","orcid":"0000-0002-6093-5444","position":6,"is_corresponding":false},{"id":676967,"name":"Kendall J Tucker","orcid":"0000-0001-5868-0449","position":0,"is_corresponding":true}],"reference_count":27,"raw_metadata":null,"created_at":"2026-07-19T01:22:08.814145Z","pmid":"38915860","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}