{"doi":"10.1016/j.semcdb.2017.08.020","title":"ESCRT-dependent cargo sorting at multivesicular endosomes","abstract":null,"journal":"Seminars in Cell & Developmental Biology","year":2018,"id":594766,"datarank":0.7755725992557229,"base_score":5.170483995038151,"endowment":5.170483995038151,"self_citation_contribution":0.7755725992557229,"citation_network_contribution":0.0,"self_endowment_contribution":0.7755725992557229,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":175,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":6,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":251453,"name":"Anjon Audhya","orcid":"0000-0002-7828-5152","position":1,"is_corresponding":false},{"id":1522711,"name":"E.B. Frankel","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"ESCRT-dependent cargo sorting at multivesicular endosomes","abstract":"The endosomal sorting complex required for transport (ESCRT) machinery is composed of five multi-subunit protein complexes, which act cooperatively at specialized endosomes to facilitate the movement of specific cargoes from the limiting membrane into vesicles that bud into the endosome lumen. Over the past decade, numerous proteins, lipids, and RNAs have been shown to be incorporated into intralumenal vesicles (ILVs), but the mechanisms by which these unique cargoes are captured are only now becoming better understood. Here, we discuss the potential roles that the ESCRT machinery plays during cargo sorting at multivesicular endosomes (MVEs).","is_dataset_classified":null,"base_score":5.170483995038151,"endowment":5.170483995038151,"datacite_reuse_total":6,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"28797838","pmcid":null,"openalex_id":"https://openalex.org/W2744528944","authors":[],"funders":[{"funder_name":"NIH","grant_id":"GM088151","title":null},{"funder_name":"NIGMS NIH HHS","grant_id":"R01 GM088151","title":null},{"funder_name":"NIGMS NIH HHS","grant_id":"R01 GM110567","title":null},{"funder_name":"NIGMS NIH HHS","grant_id":"T32 GM007215","title":null}],"total_grants":4,"fwci":6.8498,"citation_percentile":0.98029952,"influential_citations":0,"citation_trend":[{"year":2018,"count":19},{"year":2019,"count":17},{"year":2020,"count":22},{"year":2021,"count":29},{"year":2022,"count":24},{"year":2023,"count":10},{"year":2024,"count":22},{"year":2025,"count":23},{"year":2026,"count":9}],"oa_status":"green","license":"https://www.elsevier.com/tdm/userlicense/1.0/","oa_locations":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5803488","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5803488","host_type":"repository"},{"url":"https://api.elsevier.com/content/article/PII:S1084952117300113?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1084952117300113?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.semcdb.2017.08.020","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/28797838","host_type":"repository"},{"url":"http://europepmc.org/pmc/articles/PMC5803488","host_type":"repository"}],"fields_of_study":["Cellular transport and secretion","Lipid Membrane Structure and Behavior","RNA regulation and disease","Animals","Biological Transport","Endosomal Sorting Complexes Required for Transport","Endosomes","Humans","Multivesicular Bodies"],"mesh_terms":["Animals","Biological Transport","Humans","Endosomes","Endosomal Sorting Complexes Required for Transport","Multivesicular Bodies"],"keywords":["Endosome","ESCRT","Biology","Cell biology","Vesicle","Vesicular Transport Proteins","Transport protein","Protein targeting","Sorting","Vacuolar protein sorting","Membrane protein","Biochemistry","Membrane","Computer science","Cargo sorting","ESCRT machinery","Intralumenal vesicle","Multivesicular endosome","Ubiquitin"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Life below water"}],"linked_datasets":[{"doi":"10.6084/m9.figshare.14736966.v1","title":"Additional file 2 of LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation","publisher":"figshare","resource_type":"Image"},{"doi":"10.6084/m9.figshare.14736969","title":"Additional file 3 of LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation","publisher":"figshare","resource_type":"Image"},{"doi":"10.6084/m9.figshare.14736963.v1","title":"Additional file 1 of LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation","publisher":"figshare","resource_type":"Image"},{"doi":"10.6084/m9.figshare.14736966","title":"Additional file 2 of LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation","publisher":"figshare","resource_type":"Image"},{"doi":"10.6084/m9.figshare.14736969.v1","title":"Additional file 3 of LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation","publisher":"figshare","resource_type":"Image"},{"doi":"10.6084/m9.figshare.14736963","title":"Additional file 1 of LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation","publisher":"figshare","resource_type":"Image"}],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-27T15:30:07.399870Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}