{"doi":"10.1016/j.semcdb.2014.06.015","title":"Heterochrony and developmental timing mechanisms: Changing ontogenies in evolution","abstract":null,"journal":"Seminars in Cell & Developmental Biology","year":2014,"id":686587,"datarank":0.6814942173405006,"base_score":4.543294782270004,"endowment":4.543294782270004,"self_citation_contribution":0.6814942173405006,"citation_network_contribution":0.0,"self_endowment_contribution":0.6814942173405006,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":93,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":194978,"name":"Kathleen K. Smith","orcid":null,"position":1,"is_corresponding":false},{"id":1793711,"name":"Anna L. Keyte","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Heterochrony and developmental timing mechanisms: Changing ontogenies in evolution","abstract":"Heterochrony, or a change in developmental timing, is an important mechanism of evolutionary change. Historically the concept of heterochrony has focused alternatively on changes in size and shape or changes in developmental sequence, but most have focused on the pattern of change. Few studies have examined changes in the mechanisms that embryos use to actually measure time during development. Recently, evolutionary studies focused on changes in distinct timekeeping mechanisms have appeared, and this review examines two such case studies: the evolution of increased segment number in snakes and the extreme rostral to caudal gradient of developmental maturation in marsupials. In both examples, heterochronic modifications of the somite clock have been important drivers of evolutionary change.","is_dataset_classified":null,"base_score":4.543294782270004,"endowment":4.543294782270004,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"24994599","pmcid":"PMC4201350","openalex_id":"https://openalex.org/W2027303772","authors":[],"funders":[{"funder_name":"NIH NRSA","grant_id":"5F32HD070631-03","title":null},{"funder_name":"NICHD NIH HHS","grant_id":"F32 HD070631","title":null},{"funder_name":"NICHD NIH HHS","grant_id":"T32 HD040372","title":null}],"total_grants":3,"fwci":2.079,"citation_percentile":0.86981242,"influential_citations":0,"citation_trend":[{"year":2014,"count":3},{"year":2015,"count":7},{"year":2016,"count":2},{"year":2017,"count":4},{"year":2018,"count":11},{"year":2019,"count":9},{"year":2020,"count":2},{"year":2021,"count":7},{"year":2022,"count":7},{"year":2023,"count":8},{"year":2024,"count":12},{"year":2025,"count":11},{"year":2026,"count":10}],"oa_status":"green","license":"https://www.elsevier.com/tdm/userlicense/1.0/","oa_locations":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4201350","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4201350","host_type":"repository"},{"url":"https://api.elsevier.com/content/article/PII:S1084952114001888?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1084952114001888?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.semcdb.2014.06.015","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/24994599","host_type":"repository"}],"fields_of_study":["Developmental Biology and Gene Regulation","Bat Biology and Ecology Studies","Morphological variations and asymmetry","Animals","Biological Evolution","Gene Expression Regulation, Developmental","Humans","Morphogenesis","Somites"],"mesh_terms":["Animals","Biological Evolution","Humans","Morphogenesis","Gene Expression Regulation, Developmental","Somites"],"keywords":["Heterochrony","Biology","Evolutionary biology","Evolutionary developmental biology","Somite","Mechanism (biology)","Marsupial","Developmental biology","Biological evolution","Zoology","Ontogeny","Embryo","Embryogenesis","Genetics","limb","Developmental Timing","Somitogenesis","Timekeeping Mechanisms"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Life below water"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-18T19:54:47.550430Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}