{"doi":"10.1016/j.puhe.2022.03.020","title":"Relationship of resting heart rate and blood pressure with all-cause and cardiovascular disease mortality","abstract":null,"journal":"Public Health","year":2022,"id":597561,"datarank":0.3958585994422889,"base_score":2.639057329615259,"endowment":2.639057329615259,"self_citation_contribution":0.3958585994422889,"citation_network_contribution":0.0,"self_endowment_contribution":0.3958585994422889,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":13,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1436415,"name":"X. Chen","orcid":"0009-0009-0327-5118","position":1,"is_corresponding":false},{"id":728067,"name":"Z. Shi","orcid":null,"position":2,"is_corresponding":false},{"id":1460910,"name":"S. Shi","orcid":"0000-0002-2214-1440","position":3,"is_corresponding":false},{"id":538491,"name":"Q. Tian","orcid":null,"position":4,"is_corresponding":false},{"id":1318176,"name":"X. Hu","orcid":"0000-0003-1731-8835","position":5,"is_corresponding":false},{"id":517630,"name":"R. Song","orcid":"0000-0001-5771-2103","position":6,"is_corresponding":false},{"id":25561,"name":"K. Bai","orcid":"0000-0001-8508-1169","position":7,"is_corresponding":false},{"id":590875,"name":"W. Shi","orcid":null,"position":8,"is_corresponding":false},{"id":625727,"name":"J. Wang","orcid":"0000-0002-8202-6874","position":9,"is_corresponding":false},{"id":1296911,"name":"H. Li","orcid":"0009-0000-9424-9576","position":10,"is_corresponding":false},{"id":524615,"name":"J. Ding","orcid":null,"position":11,"is_corresponding":false},{"id":1530914,"name":"S. Geng","orcid":null,"position":12,"is_corresponding":false},{"id":1190461,"name":"X. Sheng","orcid":"0009-0005-2252-2357","position":13,"is_corresponding":false},{"id":532577,"name":"K. He","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Relationship of resting heart rate and blood pressure with all-cause and cardiovascular disease mortality","abstract":"<h4>Objectives</h4>This study aimed to investigate associations of resting heart rate (RHR) and blood pressure (BP) with all-cause and cardiovascular disease (CVD) mortality.<h4>Study design</h4>A retrospective cohort study.<h4>Methods</h4>A total of 67,028 Chinese participants aged ≥60 years were included in the analysis. RHR, systolic blood pressure (SBP), and diastolic blood pressure (DBP) were evaluated according to quartiles ([41-69, 70-74, 75-79, 80-127 beats/min], [80-119, 120-129, 130-139, 140-238 mm Hg], and [40-70, 71-79, 80-84, 85-133 mm Hg]). Cox proportional hazard models were used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) of all-cause and CVD mortality with RHR, SBP, and DBP. Restricted cubic splines were used to evaluate the dose-response association.<h4>Results</h4>During the 361,975 person-year follow-up, 9326 deaths were recorded, of which 5039 deaths were due to CVD. The risk of all-cause mortality was increased by 25% with the quartiles four vs quartile one of RHR (HR [95% CI]:1.25 [1.17-1.33]), and CVD mortality was increased by 32% (HR [95% CI]: 1.32 [1.22-1.44]). Similar results were observed when comparing the quartiles four vs quartile one of SBP with the risk of all-cause and CVD mortality (HRs [95% CIs]: 1.14 [1.07, 1.22] and 1.23 [1.12. 1.34]) and DBP with the risk of all-cause and CVD mortality (HRs [95% CIs]: 1.17 [1.11. 1.24] and 1.36 [1.26. 1.47]). We found linear associations of RHR, SBP, and DBP with all-cause and CVD mortality (P<sub>non-linearity</sub> >0.05), except for the approximately J-shaped association between DBP and all-cause mortality (P<sub>non-linearity</sub> = 0.008). There was a significant interaction of RHR and SBP with all-cause and CVD mortality (P<sub>interaction</sub> <0.05).<h4>Conclusions</h4>RHR and BP increased the risk of all-cause and CVD mortality, especially fast RHR combined with high SBP.","is_dataset_classified":null,"base_score":2.639057329615259,"endowment":2.639057329615259,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"35728416","pmcid":null,"openalex_id":"https://openalex.org/W4283076055","authors":[],"funders":[{"funder_name":"National Key Research and Development Program of China","grant_id":"2017YFC1307705","title":null},{"funder_name":"301 Military Hospital","grant_id":"","title":null}],"total_grants":2,"fwci":1.8457,"citation_percentile":0.86588659,"influential_citations":0,"citation_trend":[{"year":2023,"count":3},{"year":2024,"count":5},{"year":2025,"count":4},{"year":2026,"count":1}],"oa_status":"closed","license":"https://www.elsevier.com/legal/tdmrep-license","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S0033350622001032?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0033350622001032?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.puhe.2022.03.020","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/35728416","host_type":"repository"}],"fields_of_study":["Heart rate and cardiovascular health","Heart Rate Variability and Autonomic Control","Cardiac Health and Mental Health","Medicine","Blood Pressure","Cardiovascular Diseases","Heart Rate","Humans","Hypertension","Retrospective Studies","Risk Factors"],"mesh_terms":["Blood Pressure","Cardiovascular Diseases","Heart Rate","Humans","Hypertension","Retrospective Studies","Risk Factors"],"keywords":["Quartile","Medicine","Hazard ratio","Blood pressure","Internal medicine","Cardiology","Confidence interval","Proportional hazards model","Cause of death","Cohort","Cohort study","Disease","All-cause Mortality","Older Adults","Cardiovascular Disease Mortality","Resting Heart Rate"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-28T13:36:30.844593Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}