{"doi":"10.1016/j.psycom.2024.100182","title":"Does baseline psychiatric symptom severity predict well-being improvement in low-intensity mindfulness interventions?","abstract":"Regardless of baseline psychiatric symptom severity, individuals can improve from psychotherapy, including from low-intensity psychosocial treatments. We conducted a secondary analysis of a randomized trial of low-intensity mindfulness interventions to explore if and how specific indices of baseline symptom severity were associated with well-being trajectories during treatment and follow-up. In the original study, participants (N = 4, 411) with physical and mental health conditions were randomly assigned to one of two low-intensity mindfulness interventions (eight-session mindfulness-based cognitive therapy or a three-session mindfulness intervention). In this secondary analysis, we pooled across treatment groups and stratified participants into subgroups based on self-reported baseline levels of anxiety, depression, and social functioning. We used linear mixed effects models and descriptive trajectory plots to evaluate differences in well-being trajectories between subgroups. Baseline symptom severity was associated with well-being trajectory such that those with more severe anxiety, depression, or social functioning at baseline had generally lower well-being across time. All subgroups experienced initial improvement in well-being during the treatment period, though individuals with worse symptom severity tended not to sustain improvements and rebounded back towards baseline well-being levels during follow-up. These data suggest that, for individuals with more severe mental health symptoms, eight or three-session mindfulness-based interventions may still be clinically useful (as patients with more severe symptoms in this study were able to experience initial improvement in well-being from such interventions). However, for such patients, offering these mindfulness-based interventions for a longer duration may have prevented symptom rebounding.","journal":"Psychiatry Research Communications","year":2024,"id":477143,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9553,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":418744,"name":"Dustin J. Rabideau","orcid":"0000-0002-3829-7079","position":1,"is_corresponding":false},{"id":1314969,"name":"D Nolte","orcid":"0000-0002-8369-281X","position":2,"is_corresponding":false},{"id":1314970,"name":"Caylin M Faria","orcid":"0000-0001-8618-1831","position":3,"is_corresponding":false},{"id":1315450,"name":"Spencer Yunfeng Deng","orcid":null,"position":4,"is_corresponding":false},{"id":1275076,"name":"Nevita George","orcid":"0000-0002-6060-0396","position":5,"is_corresponding":false},{"id":1314971,"name":"Chelsea Boccagno","orcid":"0000-0002-7077-4066","position":6,"is_corresponding":false},{"id":1314972,"name":"Christina M. Temes","orcid":"0000-0002-0536-3447","position":7,"is_corresponding":false},{"id":994471,"name":"Masoud Kamali","orcid":"0000-0003-1453-5201","position":8,"is_corresponding":false},{"id":1315451,"name":"Nur Akpolat","orcid":null,"position":9,"is_corresponding":false},{"id":258445,"name":"Andrew A. Nierenberg","orcid":"0000-0003-2897-0458","position":10,"is_corresponding":false},{"id":594929,"name":"Louisa G. Sylvia","orcid":"0000-0002-6762-0664","position":11,"is_corresponding":false},{"id":686321,"name":"Alexandra K. Gold","orcid":"0000-0002-5090-5153","position":0,"is_corresponding":true}],"reference_count":25,"raw_metadata":null,"created_at":"2026-07-19T02:06:33.741984Z","pmid":"39391206","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}