{"doi":"10.1016/j.pnpbp.2015.10.003","title":"Altered resting-state functional connectivity of the amygdala in Chinese earthquake survivors","abstract":null,"journal":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","year":2016,"id":598717,"datarank":0.5333022092234121,"base_score":3.5553480614894135,"endowment":3.5553480614894135,"self_citation_contribution":0.5333022092234121,"citation_network_contribution":0.0,"self_endowment_contribution":0.5333022092234121,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":34,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1319507,"name":"Jianxin Zhang","orcid":"0000-0002-5572-7691","position":1,"is_corresponding":false},{"id":593323,"name":"Li Wang","orcid":"0000-0002-5570-1336","position":2,"is_corresponding":false},{"id":583253,"name":"Rui Li","orcid":"0000-0003-1448-6489","position":3,"is_corresponding":false},{"id":1534394,"name":"Wencai Zhang","orcid":null,"position":4,"is_corresponding":false},{"id":277248,"name":"Xiaoyu Zhang","orcid":"0000-0002-0951-9664","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Altered resting-state functional connectivity of the amygdala in Chinese earthquake survivors","abstract":"Posttraumatic stress disorder (PTSD) is linked to abnormal amygdala activities. This study measured amygdala functional connectivity using DSM-5 criteria. There were 33 participants in the PTSD group and 33 participants in a trauma-exposed control (TEC) group, who did not have PTSD according to the PTSD checklist of the DSM-5 (PCL-5). Our findings are as follows: (1) In the PTSD group, the amygdala had increased positive connectivity with the medial prefrontal cortex (mPFC) and hippocampus, and decreased positive connectivity with the inferior mPFC and insula. The amygdala had increased negative connectivity with the orbital prefrontal cortex and decreased negative connectivity with the insula in comparison with TEC group. (2) PCL of all participants was correlated with the connectivity between the amygdala and the mPFC, hippocampus, and insula. These regions overlapped with those identified in the between-group comparisons. However, there was no association between PCL of the PTSD group and connectivity in these regions. Abnormal functional connectivity between the amygdala and mPFC subdivisions, hippocampus, and insula reveals their importance in PTSD pathogenesis.","is_dataset_classified":null,"base_score":3.5553480614894135,"endowment":3.5553480614894135,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"26476339","pmcid":null,"openalex_id":"https://openalex.org/W2193876772","authors":[],"funders":[{"funder_name":"National Natural Science Foundation of China","grant_id":"31100746","title":null},{"funder_name":"National Natural Science Foundation of China","grant_id":"31371131","title":null},{"funder_name":"National Key Technology Research and Development Program of China","grant_id":"2013BAI08B02","title":null},{"funder_name":"Key Research Program of the Chinese Academy of Sciences","grant_id":"KJZD-EW-L04","title":null},{"funder_name":"Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences","grant_id":"","title":null}],"total_grants":5,"fwci":1.063,"citation_percentile":0.71262458,"influential_citations":0,"citation_trend":[{"year":2016,"count":2},{"year":2017,"count":2},{"year":2018,"count":5},{"year":2020,"count":4},{"year":2021,"count":7},{"year":2022,"count":3},{"year":2023,"count":8},{"year":2024,"count":1},{"year":2025,"count":1},{"year":2026,"count":1}],"oa_status":"green","license":"cc-by-nc-sa","oa_locations":[{"url":"http://ir.psych.ac.cn/handle/311026/15441","host_type":"repository"},{"url":"http://ir.psych.ac.cn/handle/311026/15441","host_type":"repository"},{"url":"https://api.elsevier.com/content/article/PII:S0278584615300476?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0278584615300476?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.pnpbp.2015.10.003","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/26476339","host_type":"repository"}],"fields_of_study":["Stress Responses and Cortisol","Functional Brain Connectivity Studies","Posttraumatic Stress Disorder Research"],"mesh_terms":["Adult","Amygdala","Brain Mapping","China","Female","Humans","Magnetic Resonance Imaging","Male","Middle Aged","Neural Pathways","Rest","Stress Disorders, Post-Traumatic","Survivors","Earthquakes"],"keywords":["Amygdala","Insula","Prefrontal cortex","Hippocampus","Psychology","Neuroscience","Functional connectivity","Posttraumatic stress","Functional magnetic resonance imaging","Clinical psychology","Cognition","Ptsd","Medial Prefrontal Cortex","Resting-state Functional Connectivity","Dsm-5"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Sustainable cities and communities"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-28T16:09:00.789440Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}