{"doi":"10.1016/j.plabm.2021.e00261","title":"SARSCoV-2 serostatus amongst vaccinated employees at a pediatric hospital system","abstract":"To gain insights on the heterogeneity of immune responses to vaccination against SARS-CoV-2 and to identify factors that could make individuals vulnerable to infection due to lack of response to vaccination, our hospital started offering free voluntary post-antibody testing against the spike protein IgG for all fully vaccinated employees. Post-vaccination response against SARS-CoV-2 was assessed using the FDA-EUA approved VITROS anti-SARS-CoV-2 IgG immunometric assay specific to the spike protein. Out of a total of 3266 antibody tests performed in fully vaccinated Texas Children's, 99.4% had a positive antibody response to the spike protein. From the 21 employees (0.6%) that had a negative response, 66.7% reported taking immunosuppressive drugs and/or biologics. Our data shows that most of the employees tested at our institution mounted an immune response to the immunogen in the vaccine. Post-vaccination antibody testing against SARS-CoV-2 can provide useful information to guide decisions about future vaccine doses.","journal":"Practical Laboratory Medicine","year":2021,"id":212415,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9635,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":489924,"name":"Izmarie Poventud‐Fuentes","orcid":"0000-0001-9748-5128","position":1,"is_corresponding":false},{"id":803130,"name":"Matthew Girotto","orcid":null,"position":2,"is_corresponding":false},{"id":803131,"name":"Jermaine Monroe","orcid":null,"position":3,"is_corresponding":false},{"id":62587,"name":"Julie A. Boom","orcid":"0000-0002-5500-117X","position":4,"is_corresponding":false},{"id":477517,"name":"George L. Delclos","orcid":"0000-0003-0201-8135","position":5,"is_corresponding":false},{"id":29028,"name":"James Versalovic","orcid":"0000-0002-5765-4385","position":6,"is_corresponding":false},{"id":255990,"name":"Sridevi Devaraj","orcid":"0000-0001-9189-7914","position":0,"is_corresponding":true}],"reference_count":5,"raw_metadata":null,"created_at":"2026-07-18T23:52:27.434608Z","pmid":"34977312","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}