{"doi":"10.1016/j.pbi.2019.11.005","title":"Chromatin domains in space and their functional implications","abstract":null,"journal":"Current Opinion in Plant Biology","year":2020,"id":605013,"datarank":1.0284640696786125,"base_score":3.5263605246161616,"endowment":3.5263605246161616,"self_citation_contribution":0.5289540786924243,"citation_network_contribution":0.49950999098618826,"self_endowment_contribution":0.5289540786924243,"citer_contribution":0.49950999098618826,"corpus_percentile":null,"corpus_rank":null,"citation_count":33,"citer_count":24,"citers_with_citation_signal":22,"citers_with_endowment":22,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":236899,"name":"Chang Liu","orcid":"0000-0003-2859-4288","position":1,"is_corresponding":false},{"id":1552501,"name":"Frédéric Pontvianne","orcid":"0000-0002-2913-4104","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Chromatin domains in space and their functional implications","abstract":"Genome organization displays functional compartmentalization. Many factors, including epigenetic modifications, transcription factors, chromatin remodelers, and RNAs, shape chromatin domains and the three-dimensional genome organization. Various types of chromatin domains with distinct epigenetic and spatial features exhibit different transcriptional activities. As part of the efforts to better understand plant functional genomics, over the past a few years, spatial distribution patterns of plant chromatin domains have been brought to light. In this review, we discuss chromatin domains associated with the nuclear periphery and the nucleolus, as well as chromatin domains staying in proximity and showing physical interactions. The functional implication of these domains is discussed, with a particular focus on the transcriptional regulation and replication timing. Finally, from a biophysical point of view, we discuss potential roles of liquid-liquid phase separation in plant nuclei in the genesis and maintenance of spatial chromatin domains.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"31881292","pmcid":null,"openalex_id":null,"authors":[],"funders":[{"funder_name":"French Laboratory of Excellence project TULIP","grant_id":"ANR-10-LABX-41","title":null},{"funder_name":"French Laboratory of Excellence project TULIP","grant_id":"ANR-11-IDEX-0002-02","title":null},{"funder_name":"ANR NucleoReg","grant_id":"ANR-15-CE12-0013-01","title":null},{"funder_name":"European Research Council","grant_id":"757600","title":"Chromatin Packing and Architectural Proteins in Plants"},{"funder_name":"French National Research Agency (ANR)","grant_id":"ANR-15-CE12-0013","title":"Transcriptional regulation by nucleolar sequestration"},{"funder_name":"French National Research Agency (ANR)","grant_id":"ANR-11-IDEX-0002","title":null}],"total_grants":6,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"green","license":"other-oa","oa_locations":[{"url":"https://univ-perp.hal.science/hal-02428536","host_type":"repository"},{"url":"https://api.elsevier.com/content/article/PII:S1369526619301141?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1369526619301141?httpAccept=text/plain","host_type":"publisher"},{"url":"https://zenodo.org/record/3976225","host_type":"repository"},{"url":"https://doi.org/10.1016/j.pbi.2019.11.005","host_type":""},{"url":"https://hal-univ-perp.archives-ouvertes.fr/hal-02428536/file/COPB_final.pdf","host_type":""},{"url":"https://pubmed.ncbi.nlm.nih.gov/31881292","host_type":""},{"url":"https://dx.doi.org/10.1016/j.pbi.2019.11.005","host_type":""},{"url":"https://univ-perp.hal.science/hal-02428536v1","host_type":""},{"url":"https://univ-perp.hal.science/hal-02428536v1/document","host_type":""},{"url":"https://zenodo.org/records/3976225","host_type":""},{"url":"http://dx.doi.org/10.1016/j.pbi.2019.11.005","host_type":""}],"fields_of_study":["0301 basic medicine","0303 health sciences","03 medical and health sciences"],"mesh_terms":["Cell Nucleus","Chromatin","Plants","Gene Expression Regulation","Epigenomics"],"keywords":["[SDV] Life Sciences [q-bio]","Cell Nucleus","Epigenomics","Gene Expression Regulation","Plants","Chromatin"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-30T01:26:04.948269Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}