{"doi":"10.1016/j.molcel.2024.07.010","title":"Two HUSH complexes connect a direct LINE to innate immunity","abstract":null,"journal":"Molecular Cell","year":2024,"id":663238,"datarank":0.10397207708399181,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.0,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":77632,"name":"Geoffrey J. Faulkner","orcid":"0000-0001-5769-4494","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Two HUSH complexes connect a direct LINE to innate immunity","abstract":"In this issue of Molecular Cell, Danac et al.<sup>1</sup> identify a second HUSH complex, HUSH2, that represses interferon-stimulated genes and, by competing for subunits with the canonical HUSH complex, couples LINE-1 (L1) retrotransposon transcription with immune activation.","is_dataset_classified":null,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"39121841","pmcid":null,"openalex_id":"https://openalex.org/W4401419587","authors":[],"funders":[{"funder_name":"Cancer Australia","grant_id":"2003170","title":null},{"funder_name":"NHMRC","grant_id":"GNT1173711","title":null},{"funder_name":"Mater Foundation","grant_id":"","title":null}],"total_grants":3,"fwci":0.1539,"citation_percentile":0.45945118,"influential_citations":0,"citation_trend":[{"year":2025,"count":1}],"oa_status":"closed","license":"http://www.elsevier.com/open-access/userlicense/1.0/","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S1097276524005860?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S1097276524005860?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.molcel.2024.07.010","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/39121841","host_type":"repository"}],"fields_of_study":["interferon and immune responses","T-cell and B-cell Immunology","vaccines and immunoinformatics approaches","Immunity, Innate","Humans","Long Interspersed Nucleotide Elements","Animals","Cell Cycle Proteins"],"mesh_terms":["Animals","Humans","Immunity, Innate","Cell Cycle Proteins","Long Interspersed Nucleotide Elements"],"keywords":["Biology","Innate immune system","Immunity","Line (geometry)","Computational biology","Immunology","Immune system"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-12T20:34:59.412574Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}