{"doi":"10.1016/j.jvsvi.2023.100048","title":"Patency and disease-free status after oncovascular resection of truncal malignancies with major vascular invasion","abstract":"INTRODUCTIONWith advances in current therapies, more patients are currently surgical candidates for oncologic resections that were previously deemed unresectable due to vascular invasion. We analyzed our institution’s outcomes of patients undergoing oncovascular resection of truncal malignancies with vascular invasion to identify factors associated with vascular reconstruction complications and oncologic recurrence.METHODSA retrospective chart review of all adult patients between January 1, 2002 and June 1, 2022 who underwent a surgical resection of a neoplasm at Northwestern Memorial Hospital and required vascular surgery intraoperative assistance was performed. Data on patient demographics, tumor anatomy and pathology, operative details, and clinical outcomes was extracted. Primary endpoints included 30-day and 1-year mortality, and 1-year primary patency of the vascular reconstruction. Secondary endpoints included vascular reintervention and tumor recurrence, both local and metastatic disease.RESULTSA total of 104 patients (43.3% females) with a mean age of 58 years were included in the study. Median follow up was 22.1 months (range 0-207). The most common tumor pathology included advanced renal cell carcinoma (n=58) and soft tissue and primary vascular sarcomas (n=24). Vascular procedures included 98 venous interventions and 6 arterial interventions. Overall 30-day mortality was 1% and 1-year mortality was 14.4%. Primary vascular patency at 1 year among patients with at least 12 months of follow up was 98.5%. No patients underwent a vascular reintervention. In total, 34 (38%) patients developed recurrent malignant disease (23.5% local and 76.5% metastatic) during the study period. Median time to tumor recurrence was 11.4 months (range 1.2-100).CONCLUSIONSOncovascular resections of truncal tumors involving major vascular structures can be safely performed with a low incidence of vascular complications, while tumor recurrence remains the major contributor to morbidity. Further investigation of factors associated with tumor recurrence in these patients may help refine surgical techniques.","journal":"JVS-Vascular Insights","year":2023,"id":389284,"datarank":0.10397207708399181,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.0,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9602,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":477809,"name":"Lara Lopes","orcid":"0000-0001-6472-4903","position":1,"is_corresponding":false},{"id":1159573,"name":"Nicole M. Melchior","orcid":null,"position":2,"is_corresponding":false},{"id":765764,"name":"Calvin L. Chao","orcid":"0000-0002-5738-3351","position":3,"is_corresponding":false},{"id":497714,"name":"Mark K. Eskandari","orcid":"0000-0002-4451-4316","position":4,"is_corresponding":false},{"id":1159123,"name":"Nicholas Lysak","orcid":"0000-0002-4439-3817","position":0,"is_corresponding":true}],"reference_count":19,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T01:18:22.323414Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}