{"doi":"10.1016/j.jvscit.2024.101697","title":"Feasibility of measuring magnetic resonance elastography-derived stiffness in human thoracic aorta and aortic dissection phantoms","abstract":"Type B aortic dissection (TBAD) represents a serious medical emergency with up to a 50% associated 5-year mortality caused by thoracic aorta, dissection-associated aneurysmal (DAA) degeneration, and rupture. Unfortunately, conventional size-related diagnostic methods cannot distinguish high-risk DAAs that benefit from surgical intervention from stable DAAs. Our goal is to use DAA stiffness measured with magnetic resonance elastography (MRE) as a biomarker to distinguish high-risk DAAs from stable DAAs. This is a feasibility study using MRE to (1) fabricate human-like geometries TBAD phantoms with different stiffnesses, (2) measure stiffness in TBAD phantoms with rheometry, and (3) demonstrate the first successful application of MRE to the thoracic aorta of a human volunteer. AD phantoms with heterogenous wall stiffness demonstrated the correlation between MRE-derived stiffness and rheometric measured stiffness. A pilot scan was performed in a healthy volunteer to test the technique's feasibility in the thoracic aorta.","journal":"Journal of Vascular Surgery Cases and Innovative Techniques","year":2024,"id":482457,"datarank":0.10397207708399181,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.0,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9582,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":936253,"name":"Faisal Fakhouri","orcid":"0000-0002-1185-8067","position":1,"is_corresponding":false},{"id":427878,"name":"Brian Raterman","orcid":"0000-0002-4162-8764","position":2,"is_corresponding":false},{"id":1319123,"name":"Ronald Lakony","orcid":null,"position":3,"is_corresponding":false},{"id":506161,"name":"Maxwell Wang","orcid":"0000-0002-9217-6593","position":4,"is_corresponding":false},{"id":1323426,"name":"Dakota Gonring","orcid":null,"position":5,"is_corresponding":false},{"id":1323015,"name":"Baqir J. Kedwai","orcid":"0000-0002-6812-9922","position":6,"is_corresponding":false},{"id":429148,"name":"Arunark Kolipaka","orcid":null,"position":7,"is_corresponding":false},{"id":1113324,"name":"Doran Mix","orcid":"0000-0001-5562-0336","position":8,"is_corresponding":false},{"id":951770,"name":"Adnan Hirad","orcid":null,"position":0,"is_corresponding":true}],"reference_count":28,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T02:07:18.280369Z","pmid":"39816441","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}