{"doi":"10.1016/j.jval.2024.02.004","title":"Economic Evaluations of Establishing Opioid Overdose Prevention Centers in 12 North American Cities: A Systematic Review","abstract":"OBJECTIVES: Overdose prevention centers (OPCs) provide a safe place where people can consume preobtained drugs under supervision so that a life-saving medical response can be provided quickly in the event of an overdose. OPCs are programs that are established in Canada and have recently become legally sanctioned in only a few United States jurisdictions. METHODS: We conducted a systematic review that summarizes and identifies gaps of economic evidence on establishing OPCs in North America to guide future expansion of OPCs. RESULTS: We included 16 final studies that were evaluated with the Consolidated Health Economic Evaluation Reporting Standards and Drummond checklists. Eight studies reported cost-effectiveness results (eg, cost per overdose avoided or cost per quality-adjusted life-year), with 6 also including cost-benefit; 5 reported only cost-benefit results, and 3 cost offsets. Health outcomes primarily included overdose mortality outcomes or HIV/hepatitis C virus infections averted. Most studies used mathematical modeling and projected OPC outcomes using the experience of a single facility in Vancouver, BC. CONCLUSIONS: OPCs were found to be cost-saving or to have favorable cost-effectiveness or cost-benefit ratios across all studies. Future studies should incorporate the experience of OPCs established in various settings and use a greater diversity of modeling designs.","journal":"Value in Health","year":2024,"id":441949,"datarank":0.32958368660043297,"base_score":2.1972245773362196,"endowment":2.1972245773362196,"self_citation_contribution":0.32958368660043297,"citation_network_contribution":0.0,"self_endowment_contribution":0.32958368660043297,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":8,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9118,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1254975,"name":"Jared A. Leff","orcid":"0000-0001-6995-6009","position":1,"is_corresponding":false},{"id":1255475,"name":"W. Norwood Lowry","orcid":null,"position":2,"is_corresponding":false},{"id":1255476,"name":"Jazmine M. Li","orcid":null,"position":3,"is_corresponding":false},{"id":1255477,"name":"Erica Onuoha","orcid":null,"position":4,"is_corresponding":false},{"id":1254976,"name":"Erminia Fardone","orcid":"0000-0001-7123-9551","position":5,"is_corresponding":false},{"id":428472,"name":"Ahmed M. Bayoumi","orcid":"0000-0002-7753-2828","position":6,"is_corresponding":false},{"id":396777,"name":"Kathryn E. McCollister","orcid":"0000-0003-4336-9791","position":7,"is_corresponding":false},{"id":350089,"name":"Sean M. Murphy","orcid":"0000-0001-9104-0670","position":8,"is_corresponding":false},{"id":311290,"name":"Bruce R. Schackman","orcid":"0000-0002-1132-2932","position":9,"is_corresponding":false},{"id":311286,"name":"Czarina N. Behrends","orcid":"0000-0003-3885-088X","position":0,"is_corresponding":true}],"reference_count":63,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T02:01:11.152920Z","pmid":"38401795","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}