{"doi":"10.1016/j.juro.2007.09.077","title":"Radical Nephrectomy for pT1a Renal Masses May be Associated With Decreased Overall Survival Compared With Partial Nephrectomy","abstract":null,"journal":"Journal of Urology","year":2008,"id":677905,"datarank":0.9866792036581572,"base_score":6.577861357721047,"endowment":6.577861357721047,"self_citation_contribution":0.9866792036581572,"citation_network_contribution":0.0,"self_endowment_contribution":0.9866792036581572,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":718,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":2,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":379550,"name":"Stephen A. Boorjian","orcid":"0000-0002-8705-6650","position":1,"is_corresponding":false},{"id":422864,"name":"Christine M. Lohse","orcid":"0000-0001-9888-7495","position":2,"is_corresponding":false},{"id":379551,"name":"Bradley C. Leibovich","orcid":"0000-0003-0043-6659","position":3,"is_corresponding":false},{"id":1185012,"name":"Eugene D. Kwon","orcid":null,"position":4,"is_corresponding":false},{"id":70207,"name":"John C. Cheville","orcid":"0000-0002-8202-6268","position":5,"is_corresponding":false},{"id":1771251,"name":"Michael L. Blute","orcid":null,"position":6,"is_corresponding":false},{"id":14133,"name":"R. Houston Thompson","orcid":"0009-0000-7536-523X","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Radical Nephrectomy for pT1a Renal Masses May be Associated With Decreased Overall Survival Compared With Partial Nephrectomy","abstract":"PURPOSE: We reviewed our surgical experience with small renal tumors, comparing overall survival in patients treated with radical and partial nephrectomy. MATERIALS AND METHODS: Using our nephrectomy registry we identified patients with sporadic, unilateral, solitary and localized renal masses 4 cm or less who underwent radical or partial nephrectomy between 1989 and 2003. Patients with a solitary kidney or impaired renal function at presentation were excluded, leaving 648 available for analysis. Overall survival was estimated using the Kaplan-Meier method and associations with death were evaluated using Cox proportional hazards regression. RESULTS: At last followup 146 patients had died of any cause and 502 were alive at a median of 7.1 years. Radical and partial nephrectomy was performed in 290 and 358 patients, respectively. In all patients radical nephrectomy was not significantly associated with death from any cause compared with partial nephrectomy (RR 1.12, p = 0.52). However, there was a significant interaction with age, leading us to stratify our analysis at the median age of 65 years. In 327 patients younger than 65 years radical nephrectomy was significantly associated with death from any cause compared with partial nephrectomy (RR 2.16, p = 0.02). The increased risk of death persisted after adjusting for year of surgery (p = 0.02), preoperative creatinine (p = 0.03), Charlson-Romano index (p = 0.04), symptoms at presentation (p = 0.02), diabetes at presentation (p = 0.03) and histology (p = 0.02). CONCLUSIONS: Our results suggest that, compared with partial nephrectomy, radical nephrectomy is associated with decreased overall survival in younger patients with small renal masses.","is_dataset_classified":null,"base_score":6.577861357721047,"endowment":6.577861357721047,"datacite_reuse_total":2,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"18076931","pmcid":null,"openalex_id":"https://openalex.org/W2041595467","authors":[],"funders":[],"total_grants":0,"fwci":48.2153,"citation_percentile":0.99927117,"influential_citations":20,"citation_trend":[{"year":2012,"count":89},{"year":2013,"count":66},{"year":2014,"count":49},{"year":2015,"count":39},{"year":2016,"count":42},{"year":2017,"count":42},{"year":2018,"count":30},{"year":2019,"count":25},{"year":2020,"count":35},{"year":2021,"count":14},{"year":2022,"count":26},{"year":2023,"count":21},{"year":2024,"count":20},{"year":2025,"count":13},{"year":2026,"count":4}],"oa_status":"closed","license":"http://www.elsevier.com/tdm/userlicense/1.0/","oa_locations":[{"url":"http://api.elsevier.com/content/article/PII:S0022534707025797?httpAccept=text/xml","host_type":"publisher"},{"url":"http://api.elsevier.com/content/article/PII:S0022534707025797?httpAccept=text/plain","host_type":"publisher"},{"url":"http://www.jurology.com/doi/pdf/10.1016/j.juro.2007.09.077","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.juro.2007.09.077","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/18076931","host_type":"repository"},{"url":"https://pubmed.ncbi.nlm.nih.gov/18554630","host_type":"repository"}],"fields_of_study":["Renal cell carcinoma treatment","Tuberous Sclerosis Complex Research","Renal and related cancers","Medicine"],"mesh_terms":["Adult","Age Factors","Aged","Aged, 80 and over","Carcinoma, Renal Cell","Female","Follow-Up Studies","Humans","Kidney Neoplasms","Male","Middle Aged","Nephrectomy","Retrospective Studies","Risk Factors","Survival Rate","Treatment Outcome"],"keywords":["Nephrectomy","Medicine","Renal function","Proportional hazards model","Surgery","Kidney","Urology","Creatinine","Internal medicine"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[{"doi":"10.6084/m9.figshare.25059468.v1","title":"Additional file 1 of Perioperative, functional, and oncological outcomes after cryoablation or partial nephrectomy for small renal masses in solitary kidneys: a systematic review and meta-analysis","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.25059468","title":"Additional file 1 of Perioperative, functional, and oncological outcomes after cryoablation or partial nephrectomy for small renal masses in solitary kidneys: a systematic review and meta-analysis","publisher":"figshare","resource_type":"JournalArticle"}],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-17T04:42:33.277378Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}