{"doi":"10.1016/j.jplph.2022.153810","title":"A novel ABA-insensitive mutant in Arabidopsis reveals molecular network of ABA-induced anthocyanin accumulation and abiotic stress tolerance","abstract":null,"journal":"Journal of Plant Physiology","year":2022,"id":590618,"datarank":0.9792441606351102,"base_score":3.1354942159291497,"endowment":3.1354942159291497,"self_citation_contribution":0.47032413238937254,"citation_network_contribution":0.5089200282457377,"self_endowment_contribution":0.47032413238937254,"citer_contribution":0.5089200282457377,"corpus_percentile":null,"corpus_rank":null,"citation_count":22,"citer_count":21,"citers_with_citation_signal":18,"citers_with_endowment":18,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1081621,"name":"Xiaojing Wang","orcid":"0000-0002-2631-4708","position":1,"is_corresponding":false},{"id":1324821,"name":"Huan Liu","orcid":"0000-0002-3264-7904","position":2,"is_corresponding":false},{"id":1511120,"name":"Zian Cai","orcid":null,"position":3,"is_corresponding":false},{"id":1511121,"name":"Cunfu Lu","orcid":null,"position":4,"is_corresponding":false},{"id":1442767,"name":"Yuzhen Chen","orcid":"0000-0002-1214-4648","position":5,"is_corresponding":false},{"id":1511119,"name":"Weijia Shi","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"A novel ABA-insensitive mutant in Arabidopsis reveals molecular network of ABA-induced anthocyanin accumulation and abiotic stress tolerance","abstract":"Abscisic acid (ABA) plays primary regulatory roles in abiotic stress tolerance and seed germination. Here, we report a unique novel Arabidopsis abscisic acid-insensitive mutant, abr (abscisic acid resistance), which was able to germinate in medium containing high ABA concentrations and tolerant to abiotic stress tolerance. We observed that abr mutant accumulated more anthocyanins by ABA treatment than did the wild type (WT). Dimethylthiourea (DMTU, an H<sub>2</sub>O<sub>2</sub> scavenger) was effective in inhibiting ABA-induced anthocyanins accumulation. RNA-seq showed that the expression of anthocyanins synthesis, antioxidant enzyme and stress-related genes were specifically increased in ABA-treated abr seedlings, suggesting that the abr mutation affects stress response as well as ABA responses. Interestingly, seedlings accumulating anthocyanins exhibited more tolerance to mannitol and NaCl compared to wild type. We propose that ABA-induced H<sub>2</sub>O<sub>2</sub> generation triggers the foliar anthocyanins accumulation, which, in turn, enhances the abiotic stress tolerance in abr mutant.","is_dataset_classified":null,"base_score":3.091042453358316,"endowment":3.091042453358316,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"36162212","pmcid":null,"openalex_id":"https://openalex.org/W4295240940","authors":[],"funders":[{"funder_name":"National Natural Science Foundation of China","grant_id":"31270737","title":null},{"funder_name":"National Key Research and Development Program of China","grant_id":"2018 YFD0600101","title":null},{"funder_name":"Beijing Forestry University","grant_id":"","title":null}],"total_grants":3,"fwci":1.4102,"citation_percentile":0.81159142,"influential_citations":0,"citation_trend":[{"year":2022,"count":1},{"year":2023,"count":6},{"year":2024,"count":7},{"year":2025,"count":4},{"year":2026,"count":3}],"oa_status":"closed","license":"https://doi.org/10.15223/policy-004","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S0176161722001961?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0176161722001961?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.jplph.2022.153810","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/36162212","host_type":"repository"}],"fields_of_study":["Plant Gene Expression Analysis","Plant Stress Responses and Tolerance","Plant Molecular Biology Research","Abscisic Acid","Anthocyanins","Antioxidants","Arabidopsis","Arabidopsis Proteins","Gene Expression Regulation, Plant","Germination","Hydrogen Peroxide","Mannitol","Mutation","Seedlings","Sodium Chloride","Stress, Physiological"],"mesh_terms":["Abscisic Acid","Anthocyanins","Antioxidants","Hydrogen Peroxide","Mannitol","Mutation","Sodium Chloride","Stress, Physiological","Arabidopsis","Gene Expression Regulation, Plant","Germination","Arabidopsis Proteins","Seedlings"],"keywords":["Abscisic acid","Abiotic stress","Anthocyanin","Mutant","Arabidopsis","Germination","Abiotic component","Wild type","Arabidopsis thaliana","Chemistry","Biology","Botany","Biochemistry","Gene","ABA","H(2)o(2)","Aba-insensitive Mutant"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-25T04:44:07.906449Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}