{"doi":"10.1016/j.jpeds.2018.10.040","title":"Detrimental Impact of Low Birth Weight on Circulating Number and Functional Capacity of Endothelial Progenitor Cells in Healthy Children: Role of Angiogenic Factors","abstract":null,"journal":"The Journal of Pediatrics","year":2019,"id":642358,"datarank":0.42498200160843247,"base_score":2.833213344056216,"endowment":2.833213344056216,"self_citation_contribution":0.42498200160843247,"citation_network_contribution":0.0,"self_endowment_contribution":0.42498200160843247,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":16,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1670738,"name":"Franciele De Meneck","orcid":null,"position":1,"is_corresponding":false},{"id":617531,"name":"Vanessa Oliveira","orcid":"0000-0002-2336-4208","position":2,"is_corresponding":false},{"id":1670739,"name":"Elisa Mieko Higa","orcid":null,"position":3,"is_corresponding":false},{"id":1670740,"name":"Eliana Hiromi Akamine","orcid":null,"position":4,"is_corresponding":false},{"id":38661,"name":"Maria do Carmo Franco","orcid":"0000-0003-0604-7689","position":5,"is_corresponding":false},{"id":1670737,"name":"Livia Victorino Souza","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Detrimental Impact of Low Birth Weight on Circulating Number and Functional Capacity of Endothelial Progenitor Cells in Healthy Children: Role of Angiogenic Factors","abstract":"<h4>Objective</h4>To provide a comprehensive assessment of the relationship of birth weight with both endothelial progenitor cell function and angiogenic factors in children.<h4>Study design</h4>Anthropometric measures, biochemical profile, endothelial progenitor cell number, endothelial progenitor cell colony-forming units, vascular endothelial growth factor-A, and nitric oxide plasma levels of 58 children aged 7-11 years were determined.<h4>Results</h4>A positive correlation was observed between birth weight and circulating endothelial progenitor cell number (r= 0.461; P= .001), endothelial progenitor cell colony-forming units (r= 0.512; P < .001), vascular endothelial growth factor-A (r= 0.407; P= .002), and nitric oxide (r= 0.547; P < .001) levels, whereas the adjustment for prematurity, family history of cardiovascular disease, and systolic blood pressure levels did not modify these associations.<h4>Conclusion</h4>Low birth weight was associated with a decrease in the circulating/functional capacity of endothelial progenitor cells among healthy children, independent of traditional cardiovascular risk factors. 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