{"doi":"10.1016/j.jjcc.2023.09.013","title":"Impact of controlled blood pressure and pulse rate at discharge on clinical outcomes in patients with ST-segment elevation myocardial infarction","abstract":null,"journal":"Journal of Cardiology","year":2024,"id":612552,"datarank":0.26876392038420827,"base_score":1.791759469228055,"endowment":1.791759469228055,"self_citation_contribution":0.26876392038420827,"citation_network_contribution":0.0,"self_endowment_contribution":0.26876392038420827,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":5,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1577288,"name":"Kenichi Sakakura","orcid":null,"position":1,"is_corresponding":false},{"id":122297,"name":"Hiroyuki Jinnouchi","orcid":null,"position":2,"is_corresponding":false},{"id":1577289,"name":"Yousuke Taniguchi","orcid":null,"position":3,"is_corresponding":false},{"id":1577290,"name":"Takunori Tsukui","orcid":null,"position":4,"is_corresponding":false},{"id":1577291,"name":"Masashi Hatori","orcid":null,"position":5,"is_corresponding":false},{"id":472756,"name":"Yusuke Watanabe","orcid":"0000-0003-2297-5303","position":6,"is_corresponding":false},{"id":630410,"name":"Kei Yamamoto","orcid":"0000-0003-2712-1550","position":7,"is_corresponding":false},{"id":1577294,"name":"Masaru Seguchi","orcid":null,"position":8,"is_corresponding":false},{"id":1184094,"name":"Hiroshi Wada","orcid":"0000-0001-8862-7833","position":9,"is_corresponding":false},{"id":1508356,"name":"Hideo Fujita","orcid":null,"position":10,"is_corresponding":false},{"id":1577287,"name":"Satomi Kobayashi","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Impact of controlled blood pressure and pulse rate at discharge on clinical outcomes in patients with ST-segment elevation myocardial infarction","abstract":"<h4>Background</h4>Although major guidelines recommend the routine introduction of angiotensin-converting enzyme (ACE) inhibitors/angiotensin receptor blockers (ARBs) and beta-blockers for patients with ST-segment elevation myocardial infarction (STEMI), evidence regarding the target blood pressure (BP) or pulse rate (PR) at hospital discharge is sparse. This retrospective study aimed to compare the clinical outcomes in patients with STEMI between those with good BP and PR control and those with poor BP or PR control.<h4>Methods</h4>We included 748 patients with STEMI who received both ACE inhibitors/ARBs and beta-blockers at hospital discharge, and divided them into a good control group (systolic BP ≤140 mmHg and PR ≤80 bpm, n = 564) and a poor control group (systolic BP >140 mmHg or PR >80 bpm, n = 184). The primary endpoint was major cardiovascular events (MACE) defined as the composite of all-cause death, non-fatal myocardial infarction, and re-admission for heart failure.<h4>Results</h4>During the median follow-up duration of 568 days, a total of 119 MACE were observed. The Kaplan-Meier curves showed that MACE were more frequently observed in the poor control group (p = 0.009). In the multivariate Cox hazard analysis, the good control group was inversely associated with MACE (HR 0.656, 95 % CI: 0.444-0.968, p = 0.034) after controlling for multiple confounding factors.<h4>Conclusions</h4>The good control of systolic BP and PR at discharge was inversely associated with long-term adverse events in STEMI patients treated with both ACE inhibitors/ARBs and beta blockers. This study suggests the importance of titration of ACE inhibitors/ARBs and beta-blockers for better clinical outcomes in patients with STEMI.","is_dataset_classified":null,"base_score":1.791759469228055,"endowment":1.791759469228055,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"37802203","pmcid":null,"openalex_id":"https://openalex.org/W4387345835","authors":[],"funders":[],"total_grants":0,"fwci":0.8861,"citation_percentile":0.76803528,"influential_citations":0,"citation_trend":[{"year":2025,"count":5}],"oa_status":"bronze","license":"http://www.elsevier.com/open-access/userlicense/1.0/","oa_locations":[{"url":"http://www.journal-of-cardiology.com/article/S0914508723002435/pdf","host_type":"journal"},{"url":"http://www.journal-of-cardiology.com/article/S0914508723002435/pdf","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0914508723002435?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0914508723002435?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.jjcc.2023.09.013","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/37802203","host_type":"repository"}],"fields_of_study":["Acute Myocardial Infarction Research","Heart rate and cardiovascular health","Blood Pressure and Hypertension Studies","Humans","ST Elevation Myocardial Infarction","Angiotensin-Converting Enzyme Inhibitors","Angiotensin Receptor Antagonists","Blood Pressure","Heart Rate","Patient Discharge","Retrospective Studies","Percutaneous Coronary Intervention","Myocardial Infarction","Adrenergic beta-Antagonists","Treatment Outcome"],"mesh_terms":["ST Elevation Myocardial Infarction","Adrenergic beta-Antagonists","Angiotensin-Converting Enzyme Inhibitors","Blood Pressure","Heart Rate","Humans","Myocardial Infarction","Patient Discharge","Retrospective Studies","Treatment Outcome","Angiotensin Receptor Antagonists","Percutaneous Coronary Intervention"],"keywords":["Mace","Medicine","Internal medicine","Cardiology","Myocardial infarction","Blood pressure","Hazard ratio","Heart failure","Clinical endpoint","Pulse pressure","Percutaneous coronary intervention","Confidence interval","Clinical trial","Acute myocardial infarction","St-elevation Myocardial Infarction","Optimal Medical Therapy"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-02T04:01:57.621539Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}