{"doi":"10.1016/j.jiph.2025.102800","title":"A systematic review and meta-analysis of the global prevalence of human enteric adenovirus infections","abstract":"Human adenovirus (HAdV), especially HAdV species F (HAdV-F) is recognized as a cause of acute gastroenteritis (AGE) worldwide. To assess the global prevalence of HAdV in case-patients of all ages with AGE, we conducted a systematic literature search for studies published in English during 2015-2022. We generated pooled prevalence estimates using generalized linear mixed models. Using data from 147 included articles, the overall pooled prevalence among AGE case-patients of any species of HAdV (pan-HAdV) was 5.8 % and 6.0 % for HAdV-F. The prevalence of HAdV was significantly higher among case-patients < 5 years of age compared with case-patients ≥ 5 years of age (pan-HAdV: 6.6 % vs. 2.0 %, p < 0.0001; HAdV-F: 8.7 % vs. 2.3 %, p = 0.04). Prevalence was significantly higher in high mortality developing countries and lowest in developed countries (pan-HAdV: 9.4 % vs. 4.0 %, p < 0.0001; HAdV-F: 11.6 % vs. 3.2 %, p = 0.0003). Understanding the burden of HAdV-associated AGE may be useful for targeted interventions, including future vaccine development.","journal":"Journal of Infection and Public Health","year":2025,"id":513320,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":10,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.8187,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":480960,"name":"Anita Kambhampati","orcid":"0000-0002-2304-073X","position":1,"is_corresponding":false},{"id":310342,"name":"Claire P. Mattison","orcid":"0000-0001-8558-8779","position":2,"is_corresponding":false},{"id":308212,"name":"Preeti Chhabra","orcid":"0000-0002-7265-2556","position":3,"is_corresponding":false},{"id":1374990,"name":"Oluwatosin Olojo","orcid":null,"position":4,"is_corresponding":false},{"id":1374991,"name":"Taha Rana","orcid":null,"position":5,"is_corresponding":false},{"id":291907,"name":"Jan Vinjé","orcid":"0000-0002-1530-3675","position":6,"is_corresponding":false},{"id":1374354,"name":"Carl D. Kirkwood","orcid":"0000-0003-2952-8135","position":7,"is_corresponding":false},{"id":245617,"name":"Umesh D. Parashar","orcid":"0000-0002-9684-9425","position":8,"is_corresponding":false},{"id":669287,"name":"Sara A. Mirza","orcid":"0000-0003-3144-6569","position":9,"is_corresponding":false},{"id":325457,"name":"Mary E. Wikswo","orcid":"0000-0001-6894-5041","position":0,"is_corresponding":true}],"reference_count":34,"raw_metadata":null,"created_at":"2026-07-19T02:48:17.908238Z","pmid":"40334566","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}