{"doi":"10.1016/j.jfms.2010.12.010","title":"Results of molecular diagnostic assays targeting feline herpesvirus-1 and feline calicivirus in adult cats administered modified live vaccines","abstract":"<jats:p>In this pilot study, 12 adult, gang-housed cats that were known to be previously exposed ( n=12) to feline herpesvirus-1 (FHV-1) and/or vaccinated against ( n=2) feline calicivirus (FCV) and FHV-1 were randomly assigned to one of two groups of six cats each. Nasal and pharyngeal samples were collected from each cat on days −7, −3, and 0 prior to vaccination and on days 3, 7, 10, 14, 17, 21, and 28 after vaccination with an FHV-1, FCV, and panleukopenia (FVRCP) vaccine developed for intranasal (six cats) or parenteral (six cats) use. FHV-1 DNA was amplified from 1/12 cats (1/69 samples; 1.4%) prior to vaccination and 2/12 cats after vaccination (2/154 samples; 1.3%). FCV RNA was amplified from 2/12 cats (2/69 samples; 2.9%) prior to vaccination and 7/12 cats (12/154 samples; 7.8%) after vaccination. Positive molecular diagnostic assay results for FHV-1 and FCV were uncommon prior to or after vaccination in these cats.</jats:p>","journal":"Journal of Feline Medicine and Surgery","year":2011,"id":596441,"datarank":0.5289540786924243,"base_score":3.5263605246161616,"endowment":3.5263605246161616,"self_citation_contribution":0.5289540786924243,"citation_network_contribution":0.0,"self_endowment_contribution":0.5289540786924243,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":33,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1527557,"name":"Julia K. Veir","orcid":null,"position":1,"is_corresponding":false},{"id":1527560,"name":"Jennifer R. Hawley","orcid":null,"position":2,"is_corresponding":false},{"id":1527561,"name":"Michael R. Lappin","orcid":null,"position":3,"is_corresponding":false},{"id":1527554,"name":"Rebecca A. Ruch-Gallie","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Results of molecular diagnostic assays targeting feline herpesvirus-1 and feline calicivirus in adult cats administered modified live vaccines","abstract":"<jats:p>In this pilot study, 12 adult, gang-housed cats that were known to be previously exposed ( n=12) to feline herpesvirus-1 (FHV-1) and/or vaccinated against ( n=2) feline calicivirus (FCV) and FHV-1 were randomly assigned to one of two groups of six cats each. Nasal and pharyngeal samples were collected from each cat on days −7, −3, and 0 prior to vaccination and on days 3, 7, 10, 14, 17, 21, and 28 after vaccination with an FHV-1, FCV, and panleukopenia (FVRCP) vaccine developed for intranasal (six cats) or parenteral (six cats) use. FHV-1 DNA was amplified from 1/12 cats (1/69 samples; 1.4%) prior to vaccination and 2/12 cats after vaccination (2/154 samples; 1.3%). FCV RNA was amplified from 2/12 cats (2/69 samples; 2.9%) prior to vaccination and 7/12 cats (12/154 samples; 7.8%) after vaccination. Positive molecular diagnostic assay results for FHV-1 and FCV were uncommon prior to or after vaccination in these cats.</jats:p>","is_dataset_classified":null,"base_score":3.5263605246161616,"endowment":3.5263605246161616,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"21439879","pmcid":"PMC10822404","openalex_id":"https://openalex.org/W1985373566","authors":[],"funders":[],"total_grants":0,"fwci":1.5877,"citation_percentile":0.819581,"influential_citations":0,"citation_trend":[{"year":2012,"count":2},{"year":2013,"count":3},{"year":2014,"count":2},{"year":2015,"count":3},{"year":2016,"count":3},{"year":2017,"count":2},{"year":2018,"count":2},{"year":2019,"count":1},{"year":2021,"count":4},{"year":2022,"count":1},{"year":2024,"count":7},{"year":2025,"count":1}],"oa_status":"green","license":"https://journals.sagepub.com/page/policies/text-and-data-mining-license","oa_locations":[{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10822404/pdf/10.1016_j.jfms.2010.12.010.pdf","host_type":"repository"},{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10822404/pdf/10.1016_j.jfms.2010.12.010.pdf","host_type":"repository"},{"url":"https://journals.sagepub.com/doi/pdf/10.1016/j.jfms.2010.12.010","host_type":"publisher"},{"url":"https://journals.sagepub.com/doi/full-xml/10.1016/j.jfms.2010.12.010","host_type":"publisher"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10822404","host_type":"repository"},{"url":"https://doi.org/10.1016/j.jfms.2010.12.010","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/21439879","host_type":"repository"}],"fields_of_study":["Herpesvirus Infections and Treatments","Virus-based gene therapy research","Viral gastroenteritis research and epidemiology","Animals","Antibodies, Viral","Caliciviridae Infections","Calicivirus, Feline","Cat Diseases","Cats","Feline Panleukopenia","Feline Panleukopenia Virus","Female","Herpesviridae Infections","Male","Nasal Mucosa","Pharynx","Pilot Projects","Polymerase Chain Reaction","RNA, Viral","Random Allocation","Respiratory Tract Infections","Varicellovirus","Viral Vaccines"],"mesh_terms":["Animals","Antibodies, Viral","Cat Diseases","Cats","Feline Panleukopenia","Female","Herpesviridae Infections","Male","Nasal Mucosa","Pharynx","Pilot Projects","Random Allocation","Respiratory Tract Infections","RNA, Viral","Viral Vaccines","Polymerase Chain Reaction","Caliciviridae Infections","Calicivirus, Feline","Varicellovirus","Feline Panleukopenia Virus","Feline panleukopenia virus"],"keywords":["Feline calicivirus","CATS","Vaccination","Medicine","Virology","Nasal administration","Feline immunodeficiency virus","Virus","Viral disease","Internal medicine","Lentivirus"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-28T10:14:59.384720Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}