{"doi":"10.1016/j.jfma.2023.11.005","title":"The predictors of long-term outcomes after targeted therapy for primary Aldosteronism","abstract":null,"journal":"Journal of the Formosan Medical Association","year":2024,"id":638308,"datarank":0.24141568686511508,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"self_citation_contribution":0.24141568686511508,"citation_network_contribution":0.0,"self_endowment_contribution":0.24141568686511508,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1657810,"name":"Shun-Chen Huang","orcid":null,"position":1,"is_corresponding":false},{"id":1657812,"name":"Chien-Ting Pan","orcid":null,"position":2,"is_corresponding":false},{"id":1657814,"name":"Kang-Yung Peng","orcid":"0000-0002-5773-676X","position":3,"is_corresponding":false},{"id":513571,"name":"Liang-Yu Lin","orcid":"0000-0003-4720-6738","position":4,"is_corresponding":false},{"id":1657817,"name":"Chieh-Kai Chan","orcid":null,"position":5,"is_corresponding":false},{"id":1657818,"name":"Chia-Tung Shun","orcid":null,"position":6,"is_corresponding":false},{"id":1657808,"name":"Ying-Ying Chen","orcid":"0000-0002-7864-8793","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"The predictors of long-term outcomes after targeted therapy for primary Aldosteronism","abstract":"Unilateral primary aldosteronism is thought to be a surgically curable disease, and unilateral adrenalectomy is the mainstay treatment. The Primary Aldosteronism Surgical Outcome (PASO) consensus was developed to assess clinical and biochemical outcomes to standardize the classification of surgical outcomes. However, fewer than half of patients are cured of hypertension after adrenalectomy; therefore, preoperative patient counseling and evaluation might be necessary. Moreover, current studies show that genetic mutations and histopathology classification are associated with the treatment outcome. The Task Force of Taiwan PA recommends using a specific scoring system, including the PASO score and nomogram-based preoperative score, to predict the clinical outcome before adrenalectomy. Herein, we discuss the associations of current histopathological classification and specific somatic gene mutations with clinical outcomes after surgery.","is_dataset_classified":null,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"38097431","pmcid":null,"openalex_id":"https://openalex.org/W4389765480","authors":[],"funders":[{"funder_name":"Ministry of Science and Technology, Taiwan","grant_id":"109-2314-B-002 -174 -MY3","title":null},{"funder_name":"Ministry of Science and Technology, Taiwan","grant_id":"111-2314-B-002 -058 -","title":null},{"funder_name":"National Taiwan University Hospital","grant_id":"112-HCH024","title":null}],"total_grants":3,"fwci":0.5974,"citation_percentile":0.71093153,"influential_citations":0,"citation_trend":[{"year":2024,"count":4}],"oa_status":"gold","license":"cc-by-nc-nd","oa_locations":[{"url":"https://doi.org/10.1016/j.jfma.2023.11.005","host_type":"journal"},{"url":"https://doi.org/10.1016/j.jfma.2023.11.005","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0929664623004710?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S0929664623004710?httpAccept=text/plain","host_type":"publisher"},{"url":"https://pubmed.ncbi.nlm.nih.gov/38097431","host_type":"repository"},{"url":"https://doaj.org/article/4aacb86063b84559a61917644c2bf2c2","host_type":"repository"}],"fields_of_study":["Hormonal Regulation and Hypertension","Adrenal and Paraganglionic Tumors","Adrenal Hormones and Disorders","Humans","Retrospective Studies","Hyperaldosteronism","Treatment Outcome","Adrenalectomy","Hypertension"],"mesh_terms":["Adrenalectomy","Humans","Hyperaldosteronism","Hypertension","Retrospective Studies","Treatment Outcome"],"keywords":["Primary aldosteronism","Medicine","Adrenalectomy","Histopathology","Nomogram","Internal medicine","Pathology","Aldosterone","Scoring System","Aldosterone-producing Adenoma","Histopathological Classification","Kcnj5 Mutation","Primary Aldosteronism Surgical Outcome (Paso)"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-06T20:27:59.954593Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}