{"doi":"10.1016/j.jebdp.2025.102140","title":"PREDICTORS OF HEALTH-RELATED QUALITY OF LIFE IN TEMPOROMANDIBULAR DISORDER PATIENTS: 8-YEAR COHORT STUDY","abstract":"• An 8-year follow-up study of 392 participants analyzed HRQoL in TMD using the SF-12. • Healthy controls: JFLS predicted mental HRQoL (MCS) but not physical HRQoL (PCS). • Nonpainful TMD: JFLS and general health predicted PCS, but no factors predicted MCS. • Painful TMD: Age and general health predicted PCS, while no factors predicted MCS. This study aimed to identify baseline factors that predict Health-Related Quality of Life (HRQoL) in patients with TMD 8 years later. 401 participants (333 women, mean age 45.8 years) from a multicenter cohort were examined using the Diagnostic Criteria for TMD (DC/TMD) and questionnaires. The main outcome was the 12-item Short Form Health Survey (SF-12), a HRQoL measure that provides physical (PCS) and mental (MCS) summaries. Baseline predictors included age, gender, self-reported health, Jaw Functional Limitation Scale (JFLS), pain intensity, pain frequency, and pain duration. Regression analysis with stepwise modeling identified predictive factors. 54.3% had painful TMD, 15.7% had nonpainful TMD, and 27.7% were healthy controls. For the painful TMD group, the regression model was significant ( R² = .25, F = 4.3, P < .01), with age and favorable general health predicting PCS scores. In the nonpainful TMD group, the model was significant ( R² = .58, F = 3.8, P < .01), with JFLS and favorable general health (predicting PCS scores. The MCS model was significant in healthy controls ( R 2 = .22 , F = 1.8 , P = . 05 ), with JFLS as only predictor. Predictors of mental HRQoL: JFLS in healthy controls, but no predictors were found in TMD groups. Predictors of physical HRQoL: General health in both TMD groups, JFLS in the nonpainful TMD group, and age in the painful TMD group.","journal":"Journal of Evidence Based Dental Practice","year":2025,"id":543426,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9506,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":63033,"name":"Birgitta Häggman‐Henrikson","orcid":"0000-0001-6088-3739","position":1,"is_corresponding":false},{"id":596400,"name":"Eric Schiffman","orcid":null,"position":2,"is_corresponding":false},{"id":321633,"name":"Thomas List","orcid":"0000-0002-9638-4648","position":3,"is_corresponding":false},{"id":1433070,"name":"IBRAHIM OGHLI","orcid":"0009-0006-0415-4893","position":0,"is_corresponding":true}],"reference_count":55,"raw_metadata":null,"created_at":"2026-07-19T02:53:04.088079Z","pmid":"40716820","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}