{"doi":"10.1016/j.jaip.2023.11.035","title":"Rates of New Peanut Allergy and Discontinuation Following Introduction in High-Risk Infants","abstract":null,"journal":"The Journal of Allergy and Clinical Immunology: In Practice","year":2024,"id":677325,"datarank":0.29188652235829704,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"self_citation_contribution":0.29188652235829704,"citation_network_contribution":0.0,"self_endowment_contribution":0.29188652235829704,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1340688,"name":"Robert Wood","orcid":"0000-0002-5622-7867","position":1,"is_corresponding":false},{"id":1769744,"name":"Joan Dunlop","orcid":null,"position":2,"is_corresponding":false},{"id":479649,"name":"Jennifer Dantzer","orcid":"0000-0002-7696-1276","position":3,"is_corresponding":false},{"id":1128124,"name":"Mihaela Plesa","orcid":null,"position":4,"is_corresponding":false},{"id":110410,"name":"Alkis Togias","orcid":"0000-0001-9009-5717","position":5,"is_corresponding":false},{"id":279472,"name":"Corinne Keet","orcid":"0000-0002-6585-239X","position":6,"is_corresponding":false},{"id":1769743,"name":"Abhilasha Banerjee","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Rates of New Peanut Allergy and Discontinuation Following Introduction in High-Risk Infants","abstract":"<h4>Background</h4>Peanut introduction guidelines recommend that infants with severe eczema and/or egg allergy consume 6 g of peanut protein weekly to prevent peanut allergy. Rates of new peanut allergy after introduction and adherence remain under study.<h4>Objective</h4>To determine compliance with peanut introduction guidelines, rates of new peanut allergy, and reasons for discontinuation of peanut consumption in a cohort of high-risk infants.<h4>Methods</h4>A prospective cohort of 4- to 11-month-old high-risk infants (defined as moderate-severe eczema or non-peanut food allergy or a first-degree relative with peanut allergy) with no prior peanut exposure who were determined to not be peanut allergic were recommended to introduce 6 g of peanut protein weekly. Participants were followed to 30 months with 2 in-person visits and monthly questionnaires.<h4>Results</h4>Two hundred seventy-seven infants were followed. At last follow-up, 245 (88%) were consuming some peanut protein with median weekly consumption of 3 g (interquartile range: 1-5 g). New peanut allergy developed in 6 (2%), with 2 of those cases consistent with food protein-induced enterocolitis syndrome. Fear of reaction in another household member was the most common reason for peanut discontinuation. Reactions to peanut after introduction in the index infant occurred in <2% of peanut-allergic siblings and in 20% of peanut-allergic parents.<h4>Conclusion</h4>We found low rates of new peanut allergy and generally low rates of peanut discontinuation after introduction in our high-risk cohort. However, families of high-risk infants require significant support with introduction, especially those with another peanut-allergic member.","is_dataset_classified":null,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"38036248","pmcid":null,"openalex_id":"https://openalex.org/W4389151967","authors":[],"funders":[{"funder_name":"NIAID NIH HHS","grant_id":"T32 AI007007","title":null},{"funder_name":"NCATS NIH HHS","grant_id":"UL1 TR002541","title":null},{"funder_name":"NCATS NIH HHS","grant_id":"UL1 TR003098","title":null},{"funder_name":"NIAID NIH HHS","grant_id":"U01 AI125290","title":null}],"total_grants":4,"fwci":0.8626,"citation_percentile":0.72367678,"influential_citations":0,"citation_trend":[{"year":2024,"count":2},{"year":2025,"count":1},{"year":2026,"count":3}],"oa_status":"closed","license":"https://www.elsevier.com/legal/tdmrep-license","oa_locations":[{"url":"https://api.elsevier.com/content/article/PII:S2213219823013041?httpAccept=text/xml","host_type":"publisher"},{"url":"https://api.elsevier.com/content/article/PII:S2213219823013041?httpAccept=text/plain","host_type":"publisher"},{"url":"https://doi.org/10.1016/j.jaip.2023.11.035","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/38036248","host_type":"repository"}],"fields_of_study":["Food Allergy and Anaphylaxis Research","Celiac Disease Research and Management","Infant Nutrition and Health"],"mesh_terms":["Allergens","Eczema","Food Hypersensitivity","Humans","Infant","Arachis","Prospective Studies","Egg Hypersensitivity","Peanut Hypersensitivity"],"keywords":["Peanut allergy","Discontinuation","Medicine","Interquartile range","Allergy","Food allergy","Cohort","Peanut butter","Pediatrics","Egg allergy","Cohort study","Immunology","Internal medicine","Food science","Biology","anaphylaxis","Food Protein–induced Enterocolitis Syndrome","Early Introduction","Food Reaction"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Zero hunger"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-17T03:59:37.508282Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}